Responsiveness to rehabilitation of balance and gait impairment in elderly with peripheral neuropathy

Antonio Caronni, Michela Picardi, Giuseppe Pintavalle, Evdoxia Aristidou, Valentina Redaelli, P. Antoniotti, Irma Sterpi, Peppino Tropea, Massimo Corbo

Research output: Contribution to journalArticle

Abstract

Elderly people with peripheral neuropathy of the lower limbs (PNLL) demonstrate a typical balance and gait impairment because of sensory ataxia. There is evidence that rehabilitation produces important gains on balance and gait. However, responsiveness to rehabilitation of balance and gait measures is unknown in PNLL. Aim of the current work is to evaluate the responsiveness to rehabilitation of balance, gait and sensory ataxia measures in elderly with PNLL. Twenty-five elderly with PNLL attending physiotherapy and occupational therapy during inpatient rehabilitation were recruited. Balance and gait measures (including static posturography, TUG test and the 10 m walking test) were administered on admission and discharge. An accelerometer secured to the trunk was used for TUG recording and static balance assessment. Static balance was tested with open and closed eyes, so as to assess sensory ataxia. Following rehabilitation, patients improved gait [admission vs discharge, mean(SD): 0.86(0.33) vs 0.98(0.32) m/s], TUG [18.7(7.8) vs 15.1(5.2) s] and turning [46.2(15.3) vs 53.3(15.3) °/s]. However, none of 12 static balance parameters derived from trunk acceleration significantly changed. Principal component analysis showed that before training, eyes closed and eyes open balance correlated with orthogonal components (one and two vs. three and four). After training, eyes open and eyes closed balance were more similar to each other being both correlated with component one. Responsiveness to rehabilitation is larger for gait than static balance measured by trunk acceleration. However, exercise can also have a beneficial effect on sensory ataxia by making eyes closed balance more similar to eyes open balance.

Original languageEnglish
JournalJournal of Biomechanics
DOIs
Publication statusPublished - Jan 1 2019

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Peripheral Nervous System Diseases
Gait
Patient rehabilitation
Rehabilitation
Lower Extremity
Ataxia
Occupational therapy
Physical therapy
Gait Ataxia
Accelerometers
Occupational Therapy
Principal component analysis
Principal Component Analysis
Walking
Inpatients
Exercise

Keywords

  • Ataxia
  • Gait
  • Polyneuropathies
  • Postural balance
  • Rehabilitation

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

Cite this

Responsiveness to rehabilitation of balance and gait impairment in elderly with peripheral neuropathy. / Caronni, Antonio; Picardi, Michela; Pintavalle, Giuseppe; Aristidou, Evdoxia; Redaelli, Valentina; Antoniotti, P.; Sterpi, Irma; Tropea, Peppino; Corbo, Massimo.

In: Journal of Biomechanics, 01.01.2019.

Research output: Contribution to journalArticle

Caronni, A, Picardi, M, Pintavalle, G, Aristidou, E, Redaelli, V, Antoniotti, P, Sterpi, I, Tropea, P & Corbo, M 2019, 'Responsiveness to rehabilitation of balance and gait impairment in elderly with peripheral neuropathy', Journal of Biomechanics. https://doi.org/10.1016/j.jbiomech.2019.07.007
Caronni, Antonio ; Picardi, Michela ; Pintavalle, Giuseppe ; Aristidou, Evdoxia ; Redaelli, Valentina ; Antoniotti, P. ; Sterpi, Irma ; Tropea, Peppino ; Corbo, Massimo. / Responsiveness to rehabilitation of balance and gait impairment in elderly with peripheral neuropathy. In: Journal of Biomechanics. 2019.
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