Restless legs syndrome and nocturnal myoclonus: Initial clinical manifestation of familial amyloid polyneuropathy

F. Salvi, P. Montagna, R. Plasmati, G. Rubboli, F. Cirignotta, M. Veilleux, E. Lugaresi, C. A. Tassinari

Research output: Contribution to journalArticle

Abstract

Restless legs syndrome was the first isolated clinical manifestation in four siblings of a family with familial amyloid polyneuropathy. Clinical and electrophysiological evidence of peripheral neuropathy appeared after a variable time interval. Polysomnography showed abnormal sleep patterns and nocturnal myoclonus in all patients. The restless legs syndrome responded favourably to clonazepam.

Original languageEnglish
Pages (from-to)522-525
Number of pages4
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume53
Issue number6
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

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