Restorative proctocolectomy for ulcerative colitis: Impact on lipid metabolism and adipose tissue and serum fatty acids

Marco Scarpa, Giovanna Romanato, Enzo Manzato, Cesare Ruffolo, Raffaella Marin, Silvia Basato, Sabina Zambon, Teresa Filosa, Silvia Zanoni, Fabio Pilon, Lino Polese, Giacomo C. Sturniolo, Davide F. D'Amico, Imerio Angriman

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this prospective study was to evaluate the changes of the metabolism of circulating and storage lipids in patients with ulcerative colitis after restorative proctocolectomy. Fifteen consecutive patients and 15 sex- and age-matched healthy controls were enrolled. Disease activity, diet, inflammatory parameters, plasma lipoprotein concentrations, and fatty acids (FA) of serum phospholipids and of the subcutaneous adipose tissue were assessed at colectomy and at ileostomy closure. In ulcerative colitis patients, total cholesterol and docosahexaenoic acid were lower than in healthy subjects (p

Original languageEnglish
Pages (from-to)279-287
Number of pages9
JournalJournal of Gastrointestinal Surgery
Volume12
Issue number2
DOIs
Publication statusPublished - 2008

Keywords

  • Cholesterol
  • Fatty acids
  • Restorative proctocolectomy
  • Ulcerative colitis

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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