Restoring abduction of paralyzed vocal cords in the cat using selective laryngeal reinnervation by phrenic motoneurons

Fausto Baldissera, Giovanna Cantarella, Gabriella Marini, Francesco Ottaviani

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this work was to reestablish the respiratory function of the paralyzed larynx through reinnervation of the posterior cricoarytenoid (PCA) muscle by phrenic motoneurons. In nine adult cats the adductor branch of the recurrent laryngeal nerve (RLN) of one side was cut and ligated, while the abductor branch was left intact. The whole RLN was then transected lower in the neck and its distal stump anastomosed to the upper branch of the phrenic nerve. Periodical laryngoscopies under ketamine anesthesia assessed that the inspiratory abduction of the paralyzed vocal cord recovered within 45 days to 60 days in all cats. Abduction was caused by reinnervation of the PCA muscle from phrenic motoneurons, ns demonstrated by electrophysiologicnl and anatomical (retrograde transport of horseradish peroxidase) testings.

Original languageEnglish
Pages (from-to)1399-1404
Number of pages6
JournalLaryngoscope
Volume96
Issue number12
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Otorhinolaryngology

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