Results of a newborn liver transplant program in the era of piggyback technique and extended donor criteria in Italy

Giuseppe Maria Ettorre, Roberto Santoro, Giovanni Vennarecci, Pasquale Lepiane, Mario Antonini, Eugenio Santoro

Research output: Contribution to journalArticle

Abstract

The aim of this study was to critically analyze the early and long-term results of a newborn liver transplantation (LTx) centre using piggyback technique (PT) without venovenous bypass and portocaval shunt in the era of extended criteria donors (ECDs). Between 2002 and 2010, a total of 229 LTx were performed in 225 patients, with the shortest as possible cold ischemia time (CIT) policy. The charts of the donors and recipients and the intraoperative data were retrospectively reviewed in order to define the feasibility of PT and surgical outcome, and longterm graft and patient survival. PT feasibility rate was 100%, with a median duration of surgery of 390 min range 210-630) and median unit of packed RBC transfused intraoperatively of 1 U (range 1-10). Median CIT was 400 min (range 130-870), and median AST peak was 403 mmol/L (range 48-16,900). ECDs graft rate was 85%. Over all primary dysfunction and non-function (PNF) rates were 7.4 and 2.2%, respectively and increased with graft steatosis >30% (Pg

Original languageEnglish
Pages (from-to)191-200
Number of pages10
JournalUpdates in Surgery
Volume63
Issue number3
DOIs
Publication statusPublished - 2011

Fingerprint

Italy
Cold Ischemia
Tissue Donors
Newborn Infant
Transplants
Liver
Graft Survival
Liver Transplantation

Keywords

  • Donor selection
  • Liver transplantation
  • Outcomes
  • Piggyback technique
  • Survival

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

Cite this

Results of a newborn liver transplant program in the era of piggyback technique and extended donor criteria in Italy. / Ettorre, Giuseppe Maria; Santoro, Roberto; Vennarecci, Giovanni; Lepiane, Pasquale; Antonini, Mario; Santoro, Eugenio.

In: Updates in Surgery, Vol. 63, No. 3, 2011, p. 191-200.

Research output: Contribution to journalArticle

Ettorre, Giuseppe Maria ; Santoro, Roberto ; Vennarecci, Giovanni ; Lepiane, Pasquale ; Antonini, Mario ; Santoro, Eugenio. / Results of a newborn liver transplant program in the era of piggyback technique and extended donor criteria in Italy. In: Updates in Surgery. 2011 ; Vol. 63, No. 3. pp. 191-200.
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