Results of dipyridamole plus atropine echo stress test for the diagnosis of coronary artery disease

Luca Lanzarini, Raffaela Fetiveau, Arnaldo Poli, Paolo Diotallevi, Paolo Barberis, Mario Previtali

Research output: Contribution to journalArticle

Abstract

Sensitivity of dipyridamole stress echocardiography (DIP-E) has been reported to be less than ideal in particular subsets of patients such as those with less severe extent of coronary artery disease (CAD). To verify if sensitivity could be improved, ATRO (1 mg in 2 minutes) was added at the end of a negative high-dose (0.84 mg/kg over 10 minutes) DIP-E in 61 consecutive patients (58 men, aged 53±7 years) evaluated for chest pain (33%) or for detection of residual ischemia after acute myocardial infarction (AMI) or previous MI (67%). DIP-E was positive in 28/61 (46%) and negative in 33/61 (54%) patients. Additional echo positivity was obtained in 18/33 (54%) patients after ATRO. Coronary arteriography was normal in 6 patients (10%); 1-vessel CAD was diagnosed in 28 (46%), 2-vessel CAD in 16 (26%) and 3-vessel CAD in 11 (18%) cases. The sensitivity for CAD diagnosis was 49% (27/55) for DIP-E and 84% (46/55) for DIP-E + ATRO (p

Original languageEnglish
Pages (from-to)233-240
Number of pages8
JournalThe International Journal of Cardiac Imaging
Volume11
Issue number4
DOIs
Publication statusPublished - Dec 1995

Keywords

  • atropine
  • dipyridamole
  • stress echocardiography

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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