Reticulohistiocytosis: Different dermatoscopic faces and a good response to methotrexate treatment: Clinical dermatology • Concise report

N. Kaçar, L. Tasli, G. Argenziano, N. Demirkan

Research output: Contribution to journalArticle

Abstract

The reticulohistiocytoses are a rare group of non-Langerhans cell histiocytic disorders. Recently, dermatoscopic features have been reported for some of the xanthomatous disorders. We report a case of diffuse cutaneous reticulohistiocytosis with 29 reticulohistiocytomas. On dermatoscopy of these lesions, we saw three typical features: a homogeneous pattern with various shades of yellow (defined previously as a 'setting-sun' pattern), brown reticular structures, and central white scar-like patches and streaks. The setting-sun pattern was most commonly seen in combination with brown reticular structures. In four lesions, brown reticular structures surrounded a central white scar-like patch resembling that of a dermatofibroma. However, the presence of the setting-sun pattern in the background gave a different hue to that of the peripheral network seen in a dermatofibroma. A marked clinical improvement was associated with 6 months of systemic methotrexate treatment. Dermatoscopy may aid in the diagnosis of xanthomatous diseases. For this patient, methotrexate was beneficial.

Original languageEnglish
JournalClinical and Experimental Dermatology
Volume35
Issue number4
DOIs
Publication statusPublished - Jun 2010

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Reticulohistiocytosis: Different dermatoscopic faces and a good response to methotrexate treatment: Clinical dermatology • Concise report'. Together they form a unique fingerprint.

  • Cite this