Retinal nerve fiber layer evaluation by optical coherence tomography in Leber's hereditary optic neuropathy

Piero Barboni; Giacomo Savini; Maria Lucia Valentino; Pasquale Montagna; Pietro Cortelli; Anna Maria De Negri; Federico Sadun; Stefania Bianchi; Lora Longanesi; Maurizio Zanini; Antonello De Vivo; Valerio Carelli

doi:10.1016/j.ophtha.2004.06.034

Retinal nerve fiber layer evaluation by optical coherence tomography in Leber's hereditary optic neuropathy

Piero Barboni, Giacomo Savini, Maria Lucia Valentino, Pasquale Montagna, Pietro Cortelli, Anna Maria De Negri, Federico Sadun, Stefania Bianchi, Lora Longanesi, Maurizio Zanini, Antonello De Vivo, Valerio Carelli

Research output: Contribution to journal › Article › peer-review

Abstract

To study retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (StratusOCT) in patients with Leber's hereditary optic neuropathy (LHON). Cross-sectional study. Thirty-eight patients with LHON were analyzed and compared with an age-matched control group of 75 patients. Patients with LHON were classified as having early LHON (E-LHON, n = 8) when the duration of the disease was shorter than 6 months and atrophic LHON (A-LHON, n = 30) when the duration was longer than 6 months. The fast RNFL thickness (3.4) scan acquisition protocol was used. Retinal nerve fiber layer thickness as measured by StratusOCT. Compared with the control group, eyes with E-LHON showed a thicker RNFL in the 360° average measurement (P

Original language	English
Pages (from-to)	120-126
Number of pages	7
Journal	Ophthalmology
Volume	112
Issue number	1
DOIs	https://doi.org/10.1016/j.ophtha.2004.06.034
Publication status	Published - Jan 2005

ASJC Scopus subject areas

Ophthalmology

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Retinal nerve fiber layer evaluation by optical coherence tomography in Leber's hereditary optic neuropathy. / Barboni, Piero; Savini, Giacomo; Valentino, Maria Lucia; Montagna, Pasquale; Cortelli, Pietro; De Negri, Anna Maria; Sadun, Federico; Bianchi, Stefania; Longanesi, Lora; Zanini, Maurizio; De Vivo, Antonello; Carelli, Valerio.

In: Ophthalmology, Vol. 112, No. 1, 01.2005, p. 120-126.

Research output: Contribution to journal › Article › peer-review

Barboni, Piero ; Savini, Giacomo ; Valentino, Maria Lucia ; Montagna, Pasquale ; Cortelli, Pietro ; De Negri, Anna Maria ; Sadun, Federico ; Bianchi, Stefania ; Longanesi, Lora ; Zanini, Maurizio ; De Vivo, Antonello ; Carelli, Valerio. / Retinal nerve fiber layer evaluation by optical coherence tomography in Leber's hereditary optic neuropathy. In: Ophthalmology. 2005 ; Vol. 112, No. 1. pp. 120-126.

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title = "Retinal nerve fiber layer evaluation by optical coherence tomography in Leber's hereditary optic neuropathy",

abstract = "To study retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (StratusOCT) in patients with Leber's hereditary optic neuropathy (LHON). Cross-sectional study. Thirty-eight patients with LHON were analyzed and compared with an age-matched control group of 75 patients. Patients with LHON were classified as having early LHON (E-LHON, n = 8) when the duration of the disease was shorter than 6 months and atrophic LHON (A-LHON, n = 30) when the duration was longer than 6 months. The fast RNFL thickness (3.4) scan acquisition protocol was used. Retinal nerve fiber layer thickness as measured by StratusOCT. Compared with the control group, eyes with E-LHON showed a thicker RNFL in the 360° average measurement (P",

author = "Piero Barboni and Giacomo Savini and Valentino, {Maria Lucia} and Pasquale Montagna and Pietro Cortelli and {De Negri}, {Anna Maria} and Federico Sadun and Stefania Bianchi and Lora Longanesi and Maurizio Zanini and {De Vivo}, Antonello and Valerio Carelli",

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AU - Cortelli, Pietro

AU - De Negri, Anna Maria

AU - Sadun, Federico

AU - Bianchi, Stefania

AU - Longanesi, Lora

AU - Zanini, Maurizio

AU - De Vivo, Antonello

AU - Carelli, Valerio

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