Abstract
Retinoblastoma is the most frequently diagnosed intraocular malignancy in infants. Recently, there have been significant advances in the management of this disease. New therapeutic strategies, such as superselective intra-arterial chemotherapy and periocular/intravitreal chemotherapy, have been added to conservative treatments with a long consolidated efficacy. All these procedures are available at the Referral Centre for Retinoblastoma of the University Hospital of Siena. These advances have been reflected in increased rates of eye salvage and improved visual outcomes, notwithstanding the primary objective to safeguard the lives of affected children. This article summarizes the most important clinical and therapeutic aspects of this malignancy that every paediatrician should be aware of, particularly when retinoblastoma is suspected in a young patient.
| Original language | Italian |
|---|---|
| Pages (from-to) | 227-236 |
| Number of pages | 10 |
| Journal | Medico e Bambino |
| Volume | 32 |
| Issue number | 4 |
| Publication status | Published - Apr 2013 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Il retinoblastoma. / D'ambrosio, Alfonso; Coriolani, Gianni; Caini, Mauro; Galimberti, Daniela; Giomi, Sara; Badii, Silvia; Moretti, Silvia; Toti, Maria Stefania; Coccina, Francesca; Carra, Federica; Hadjistilianou, Theodora.
In: Medico e Bambino, Vol. 32, No. 4, 04.2013, p. 227-236.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Il retinoblastoma
AU - D'ambrosio, Alfonso
AU - Coriolani, Gianni
AU - Caini, Mauro
AU - Galimberti, Daniela
AU - Giomi, Sara
AU - Badii, Silvia
AU - Moretti, Silvia
AU - Toti, Maria Stefania
AU - Coccina, Francesca
AU - Carra, Federica
AU - Hadjistilianou, Theodora
PY - 2013/4
Y1 - 2013/4
N2 - Retinoblastoma is the most frequently diagnosed intraocular malignancy in infants. Recently, there have been significant advances in the management of this disease. New therapeutic strategies, such as superselective intra-arterial chemotherapy and periocular/intravitreal chemotherapy, have been added to conservative treatments with a long consolidated efficacy. All these procedures are available at the Referral Centre for Retinoblastoma of the University Hospital of Siena. These advances have been reflected in increased rates of eye salvage and improved visual outcomes, notwithstanding the primary objective to safeguard the lives of affected children. This article summarizes the most important clinical and therapeutic aspects of this malignancy that every paediatrician should be aware of, particularly when retinoblastoma is suspected in a young patient.
AB - Retinoblastoma is the most frequently diagnosed intraocular malignancy in infants. Recently, there have been significant advances in the management of this disease. New therapeutic strategies, such as superselective intra-arterial chemotherapy and periocular/intravitreal chemotherapy, have been added to conservative treatments with a long consolidated efficacy. All these procedures are available at the Referral Centre for Retinoblastoma of the University Hospital of Siena. These advances have been reflected in increased rates of eye salvage and improved visual outcomes, notwithstanding the primary objective to safeguard the lives of affected children. This article summarizes the most important clinical and therapeutic aspects of this malignancy that every paediatrician should be aware of, particularly when retinoblastoma is suspected in a young patient.
KW - Chemotherapy
KW - Genetics
KW - Intra-arterial Melphalan
KW - Leucocoria
KW - Retinoblastoma
UR - http://www.scopus.com/inward/record.url?scp=84877728050&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84877728050&partnerID=8YFLogxK
M3 - Articolo
VL - 32
SP - 227
EP - 236
JO - Medico e Bambino
JF - Medico e Bambino
SN - 1591-3090
IS - 4
ER -