Abstract
The effect of various concentrations of retinoic acid on the growth of committed granulomonopoietic precursors (CFU-GM) was studied on semisolid agar cultures. Retinoic acid increased the growth of day 14 CFU-GM but had no significant effect on day 7 CFU-GM. Since the latter are believed to represent the progeny of day 14 CFU-GM it is suggested that the effect of retinoic acid is confined to the early stages of granulomonocytic differentiation.
Original language | English |
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Pages (from-to) | 97-99 |
Number of pages | 3 |
Journal | Acta Haematologica |
Volume | 71 |
Issue number | 2 |
Publication status | Published - 1984 |
Keywords
- CFU-GM
- Differentation
- Granulopoiesis
- Leukemia
- Retinoic acid
ASJC Scopus subject areas
- Hematology