Abstract
The effect of various concentrations of retinoic acid on the growth of committed granulomonopoietic precursors (CFU-GM) was studied on semisolid agar cultures. Retinoic acid increased the growth of day 14 CFU-GM but had no significant effect on day 7 CFU-GM. Since the latter are believed to represent the progeny of day 14 CFU-GM it is suggested that the effect of retinoic acid is confined to the early stages of granulomonocytic differentiation.
| Original language | English |
|---|---|
| Pages (from-to) | 97-99 |
| Number of pages | 3 |
| Journal | Acta Haematologica |
| Volume | 71 |
| Issue number | 2 |
| Publication status | Published - 1984 |
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Keywords
- CFU-GM
- Differentation
- Granulopoiesis
- Leukemia
- Retinoic acid
ASJC Scopus subject areas
- Hematology
Cite this
Retinoic acid enhances the growth of only one subpopulation of granulomonocyte precursors. / Aglietla, Massimo; Piacibello, Wanda; Sanavio, Fiorella; Visconli, Antonio; Gavosto, Felice.
In: Acta Haematologica, Vol. 71, No. 2, 1984, p. 97-99.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Retinoic acid enhances the growth of only one subpopulation of granulomonocyte precursors
AU - Aglietla, Massimo
AU - Piacibello, Wanda
AU - Sanavio, Fiorella
AU - Visconli, Antonio
AU - Gavosto, Felice
PY - 1984
Y1 - 1984
N2 - The effect of various concentrations of retinoic acid on the growth of committed granulomonopoietic precursors (CFU-GM) was studied on semisolid agar cultures. Retinoic acid increased the growth of day 14 CFU-GM but had no significant effect on day 7 CFU-GM. Since the latter are believed to represent the progeny of day 14 CFU-GM it is suggested that the effect of retinoic acid is confined to the early stages of granulomonocytic differentiation.
AB - The effect of various concentrations of retinoic acid on the growth of committed granulomonopoietic precursors (CFU-GM) was studied on semisolid agar cultures. Retinoic acid increased the growth of day 14 CFU-GM but had no significant effect on day 7 CFU-GM. Since the latter are believed to represent the progeny of day 14 CFU-GM it is suggested that the effect of retinoic acid is confined to the early stages of granulomonocytic differentiation.
KW - CFU-GM
KW - Differentation
KW - Granulopoiesis
KW - Leukemia
KW - Retinoic acid
UR - http://www.scopus.com/inward/record.url?scp=0021347722&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021347722&partnerID=8YFLogxK
M3 - Article
C2 - 6421061
AN - SCOPUS:0021347722
VL - 71
SP - 97
EP - 99
JO - Acta Haematologica
JF - Acta Haematologica
SN - 0001-5792
IS - 2
ER -