Sindrome da acido retinoico: grave insufficienza respiratoria trattata con ventilazione in maschera con CPAP.

Translated title of the contribution: Retinoic acid syndrome. Severe respiratory insufficiency treated with CPAP

C. Tommasino, L. De Felice, S. Colombo, D. Salaris, T. Capocasa, D. Giudici

Research output: Contribution to journalArticlepeer-review

Abstract

Retinoic acid syndrome is a potentially life-threatening complication of therapy for acute promyelocytic leukemia (APL) with all-transretinoic acid (ATRA). The case of a 55-year old male patient admitted to the hospital because of a bleeding diathesis is reported. APL was diagnosed and he underwent treatment with idarubicin and ATRA (GIMEMA protocol); 24 hrs after ATRA treatment he developed retinoic acid syndrome and was admitted to the Intensive Care Unit because of severe respiratory insufficiency (dyspnoea, tachypnea and severe hypoxemia (SpO2 75%). Pulmonary insufficiency was treated non-invasively with CPAP and the patient recovered from pulmonary distress one week later.

Translated title of the contributionRetinoic acid syndrome. Severe respiratory insufficiency treated with CPAP
Original languageItalian
Pages (from-to)555-559
Number of pages5
JournalMinerva Anestesiologica
Volume66
Issue number7-8
Publication statusPublished - Jul 2000

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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