Retrograde memory deficits in severe closed-head injury patients

Giovanni A. Carlesimo, Maurizio Sabbadini, Patrizia Bombardi, Ester Di Porto, Antonella Loasses, Carlo Caltagirone

Research output: Contribution to journalArticlepeer-review

Abstract

A battery of tests evaluating different aspects of retrograde memory (autobiographical, public events, semantic knowledge) was administered to a group of 20 patients who had suffered from a severe closed-head injury (CHI) and who had recovered from the post-traumatic amnesia period and to a group of sex-, age- and education-matched normal controls. Results document a high prevalence of retrograde memory deficits among CHI individuals. The deficit involves both autobiographical and public events memories and extends to early acquired basic and cultural knowledge. The severity of the deficit does not vary according to some kind of temporal gradient or according to a presumed hierarchical or modality organization of the semantic system. However, in the domain of basic knowledge it more severely affects information pertaining to living than nonliving categories of objects. With the exception of a more severe deficit in retrieving autobiographical events occurred in the last year before trauma in a subgroup of patients with focal lesions restricted to the right hemisphere as compared to left lesioned patients, no clear relationship emerges between severity of the retrograde memory deficit and locus of focal cerebral lesions as demonstrated by neuroradiological exams.

Original languageEnglish
Pages (from-to)1-23
Number of pages23
JournalCortex
Volume34
Issue number1
Publication statusPublished - 1998

Keywords

  • Head trauma
  • Memory
  • Semantic system

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology
  • Cognitive Neuroscience
  • Neuroscience(all)

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