Retrospective investigation of an influenza A/H1N1pdm outbreak in an Italian military ship cruising in the Mediterranean Sea, May-September 2009

Mario Tarabbo, Daniele Lapa, Concetta Castilletti, Pietro Tommaselli, Riccardo Guarducci, Giuditta Lucà, Alessandro Emanuele, Onofrio Zaccaria, Vincenzo F P La Gioia, Enrico Girardi, Maria R. Capobianchi, Giuseppe Ippolito

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: Clinical surveillance may have underestimated the real extent of the spread of the new strain of influenza A/ H1N1, which surfaced in April 2009 originating the first influenza pandemic of the 21st century. Here we report a serological investigation on an influenza A/H1N1pdm outbreak in an Italian military ship while cruising in the Mediterranean Sea (May 24-September 6, 2009). Methods: The contemporary presence of HAI and CF antibodies was used to retrospectively estimate the extent of influenza A/H1N1pdm spread across the crew members (median age: 29 years). Findings: During the cruise, 2 crew members fulfilled the surveillance case definition for influenza, but only one was laboratory confirmed by influenza A/H1N1pdm-specific RT-PCR; 52 reported acute respiratory illness (ARI) episodes, and 183 reported no ARI episodes. Overall, among the 211 crew member for whom a valid serological result was available, 39.3% tested seropositive for influenza A/H1N1pdm. The proportion of seropositives was significantly associated with more crowded living quarters and tended to be higher in those aged

Original languageEnglish
Article numbere15933
JournalPLoS One
Volume6
Issue number1
DOIs
Publication statusPublished - 2011

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Mediterranean Sea
Ships
ships
influenza
Human Influenza
Disease Outbreaks
Antibodies
monitoring
Pandemics
pandemic
reverse transcriptase polymerase chain reaction
Polymerase Chain Reaction
antibodies

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Retrospective investigation of an influenza A/H1N1pdm outbreak in an Italian military ship cruising in the Mediterranean Sea, May-September 2009. / Tarabbo, Mario; Lapa, Daniele; Castilletti, Concetta; Tommaselli, Pietro; Guarducci, Riccardo; Lucà, Giuditta; Emanuele, Alessandro; Zaccaria, Onofrio; La Gioia, Vincenzo F P; Girardi, Enrico; Capobianchi, Maria R.; Ippolito, Giuseppe.

In: PLoS One, Vol. 6, No. 1, e15933, 2011.

Research output: Contribution to journalArticle

Tarabbo, Mario ; Lapa, Daniele ; Castilletti, Concetta ; Tommaselli, Pietro ; Guarducci, Riccardo ; Lucà, Giuditta ; Emanuele, Alessandro ; Zaccaria, Onofrio ; La Gioia, Vincenzo F P ; Girardi, Enrico ; Capobianchi, Maria R. ; Ippolito, Giuseppe. / Retrospective investigation of an influenza A/H1N1pdm outbreak in an Italian military ship cruising in the Mediterranean Sea, May-September 2009. In: PLoS One. 2011 ; Vol. 6, No. 1.
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