Return to Sport Activity After Meniscal Allograft Transplantation: At What Level and at What Cost? A Systematic Review and Meta-analysis

Alberto Grassi, James R Bailey, Giuseppe Filardo, Kristian Samuelsson, Stefano Zaffagnini, Annunziato Amendola

Research output: Contribution to journalArticle

Abstract

CONTEXT:: Meniscal injuries are common among both sport- and non-sport-related injuries, with over 1.7 million meniscal surgeries performed worldwide every year. As meniscal surgeries become more common, so does meniscal allograft transplantation (MAT). However, little is known about the outcomes of MAT in active patients who desire to go back to preinjury activities.

OBJECTIVE:: The purpose of this systematic review and meta-analysis was to evaluate return to sport, clinical outcome, and complications after MAT in sport-active patients.

DATA SOURCES:: A systematic search of MEDLINE, EMBASE, and CINAHL electronic databases was performed on February 25, 2018.

STUDY SELECTION:: Studies of level 1 through 4 evidence looking at MAT in physically active patients with reported return to activity outcomes and at least 2-year follow-up were included.

STUDY DESIGN:: Systematic review and meta-analysis.

LEVEL OF EVIDENCE:: Level 4.

DATA EXTRACTION:: Details of sport-related outcomes and reoperations were extracted and pooled in a meta-analysis.

RESULTS:: Nine studies were included in this systematic review. A majority (77%) of athletes and physically active patients were able to return to sport after MAT; two-thirds were able to perform at preinjury levels. Graft-related reoperations were reported in 13% of patients, while the joint replacement rate with partial or total knee prosthesis was 1.2%.

CONCLUSION:: Physical activity after MAT appears possible, especially for low-impact sports. However, because of the limited number of studies, their low quality, and the short-term follow-up, the participation recommendation for high-impact and strenuous activities should be considered with caution until high-quality evidence of long-term safety becomes available.

Original languageEnglish
Pages (from-to)123-133
Number of pages11
JournalSports Health
Volume11
Issue number2
DOIs
Publication statusE-pub ahead of print - Jan 14 2019

Fingerprint

Allografts
Meta-Analysis
Transplantation
Costs and Cost Analysis
Sports
Reoperation
Replacement Arthroplasties
Knee Prosthesis
Wounds and Injuries
MEDLINE
Athletes
Return to Sport
Databases
Exercise
Transplants
Safety

Keywords

  • allograft
  • meniscal transplant
  • meniscectomy
  • postmeniscectomy syndrome
  • return to play
  • sport

Cite this

Return to Sport Activity After Meniscal Allograft Transplantation: At What Level and at What Cost? A Systematic Review and Meta-analysis. / Grassi, Alberto; Bailey, James R; Filardo, Giuseppe; Samuelsson, Kristian; Zaffagnini, Stefano; Amendola, Annunziato.

In: Sports Health, Vol. 11, No. 2, 14.01.2019, p. 123-133.

Research output: Contribution to journalArticle

Grassi, Alberto ; Bailey, James R ; Filardo, Giuseppe ; Samuelsson, Kristian ; Zaffagnini, Stefano ; Amendola, Annunziato. / Return to Sport Activity After Meniscal Allograft Transplantation: At What Level and at What Cost? A Systematic Review and Meta-analysis. In: Sports Health. 2019 ; Vol. 11, No. 2. pp. 123-133.
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AU - Grassi, Alberto

AU - Bailey, James R

AU - Filardo, Giuseppe

AU - Samuelsson, Kristian

AU - Zaffagnini, Stefano

AU - Amendola, Annunziato

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N2 - CONTEXT:: Meniscal injuries are common among both sport- and non-sport-related injuries, with over 1.7 million meniscal surgeries performed worldwide every year. As meniscal surgeries become more common, so does meniscal allograft transplantation (MAT). However, little is known about the outcomes of MAT in active patients who desire to go back to preinjury activities.OBJECTIVE:: The purpose of this systematic review and meta-analysis was to evaluate return to sport, clinical outcome, and complications after MAT in sport-active patients.DATA SOURCES:: A systematic search of MEDLINE, EMBASE, and CINAHL electronic databases was performed on February 25, 2018.STUDY SELECTION:: Studies of level 1 through 4 evidence looking at MAT in physically active patients with reported return to activity outcomes and at least 2-year follow-up were included.STUDY DESIGN:: Systematic review and meta-analysis.LEVEL OF EVIDENCE:: Level 4.DATA EXTRACTION:: Details of sport-related outcomes and reoperations were extracted and pooled in a meta-analysis.RESULTS:: Nine studies were included in this systematic review. A majority (77%) of athletes and physically active patients were able to return to sport after MAT; two-thirds were able to perform at preinjury levels. Graft-related reoperations were reported in 13% of patients, while the joint replacement rate with partial or total knee prosthesis was 1.2%.CONCLUSION:: Physical activity after MAT appears possible, especially for low-impact sports. However, because of the limited number of studies, their low quality, and the short-term follow-up, the participation recommendation for high-impact and strenuous activities should be considered with caution until high-quality evidence of long-term safety becomes available.

AB - CONTEXT:: Meniscal injuries are common among both sport- and non-sport-related injuries, with over 1.7 million meniscal surgeries performed worldwide every year. As meniscal surgeries become more common, so does meniscal allograft transplantation (MAT). However, little is known about the outcomes of MAT in active patients who desire to go back to preinjury activities.OBJECTIVE:: The purpose of this systematic review and meta-analysis was to evaluate return to sport, clinical outcome, and complications after MAT in sport-active patients.DATA SOURCES:: A systematic search of MEDLINE, EMBASE, and CINAHL electronic databases was performed on February 25, 2018.STUDY SELECTION:: Studies of level 1 through 4 evidence looking at MAT in physically active patients with reported return to activity outcomes and at least 2-year follow-up were included.STUDY DESIGN:: Systematic review and meta-analysis.LEVEL OF EVIDENCE:: Level 4.DATA EXTRACTION:: Details of sport-related outcomes and reoperations were extracted and pooled in a meta-analysis.RESULTS:: Nine studies were included in this systematic review. A majority (77%) of athletes and physically active patients were able to return to sport after MAT; two-thirds were able to perform at preinjury levels. Graft-related reoperations were reported in 13% of patients, while the joint replacement rate with partial or total knee prosthesis was 1.2%.CONCLUSION:: Physical activity after MAT appears possible, especially for low-impact sports. However, because of the limited number of studies, their low quality, and the short-term follow-up, the participation recommendation for high-impact and strenuous activities should be considered with caution until high-quality evidence of long-term safety becomes available.

KW - allograft

KW - meniscal transplant

KW - meniscectomy

KW - postmeniscectomy syndrome

KW - return to play

KW - sport

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VL - 11

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JO - Sports Health

JF - Sports Health

SN - 1941-7381

IS - 2

ER -