Reversal of severe parenteral nutrition-associated liver disease in an infant with short bowel syndrome using parenteral fish oil (Omega-3 fatty acids)

George Ekema, Diego Falchetti, Giovanni Boroni, Anna Rita Tanca, Cristian Altana, Laura Righetti, Michela Ridella, Marco Gambarotti, Luisa Berchich

Research output: Contribution to journalArticlepeer-review

Abstract

Total parenteral nutrition is an important adjunct in the care of neonates with surgical disorders. Cholestasis is at present the most worrisome complication of this technique; it is difficult to treat and may progress to eventual cirrhosis and liver failure. This article reviews the pertinent clinical and nutritional data in a surgical patient with short bowel syndrome who developed parenteral nutrition-associated liver disease successfully treated with fish-oil based lipids.

Original languageEnglish
Pages (from-to)1191-1195
Number of pages5
JournalJournal of Pediatric Surgery
Volume43
Issue number6
DOIs
Publication statusPublished - Jun 2008

Keywords

  • Omega-3 fatty acids
  • Parenteral nutrition-associated cholestasis (PNAC)
  • Short bowel syndrome

ASJC Scopus subject areas

  • Surgery

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