Abstract
Left ventricular function was evaluated in 24 women who developed impaired glucose tolerance only during their pregnancy, i.e. patients with gestational diabetes. The results were compared with those of 25 normal pregnant women and with those of 17 pregnant women with clinical diabetes. The method of systolic time intervals was applied. At the third trimester of pregnancy, both the women with overt diabetes and those with gestational diabetes, when compared with normal pregnant subjects, had a more prolonged prejection period (PEP) and a shorter left ventricular ejection time (LVET) and, consequently, a higher PEP/LVET ratio. Five weeks after delivery, abnormalities of systolic time intervals persisted in patients with clinical diabetes, but there were no differences at this time between patients with gestational diabetes and those in the control group. It is concluded that when a cardiac load is superimposed on patients who develop diabetes only under conditions of stress, as in pregnancy (gestational diabetes), abnormalities of myocardial function appear, which revert to normal when the stressful event is removed.
| Original language | English |
|---|---|
| Pages (from-to) | 59-63 |
| Number of pages | 5 |
| Journal | European Heart Journal |
| Volume | 4 |
| Issue number | 1 |
| Publication status | Published - 1983 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Reversible alteration of myocardial function in gestational diabetes. / Cellina, G.; Lo Cicero, G.; Brina, A.; Zanchetti, A.
In: European Heart Journal, Vol. 4, No. 1, 1983, p. 59-63.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Reversible alteration of myocardial function in gestational diabetes
AU - Cellina, G.
AU - Lo Cicero, G.
AU - Brina, A.
AU - Zanchetti, A.
PY - 1983
Y1 - 1983
N2 - Left ventricular function was evaluated in 24 women who developed impaired glucose tolerance only during their pregnancy, i.e. patients with gestational diabetes. The results were compared with those of 25 normal pregnant women and with those of 17 pregnant women with clinical diabetes. The method of systolic time intervals was applied. At the third trimester of pregnancy, both the women with overt diabetes and those with gestational diabetes, when compared with normal pregnant subjects, had a more prolonged prejection period (PEP) and a shorter left ventricular ejection time (LVET) and, consequently, a higher PEP/LVET ratio. Five weeks after delivery, abnormalities of systolic time intervals persisted in patients with clinical diabetes, but there were no differences at this time between patients with gestational diabetes and those in the control group. It is concluded that when a cardiac load is superimposed on patients who develop diabetes only under conditions of stress, as in pregnancy (gestational diabetes), abnormalities of myocardial function appear, which revert to normal when the stressful event is removed.
AB - Left ventricular function was evaluated in 24 women who developed impaired glucose tolerance only during their pregnancy, i.e. patients with gestational diabetes. The results were compared with those of 25 normal pregnant women and with those of 17 pregnant women with clinical diabetes. The method of systolic time intervals was applied. At the third trimester of pregnancy, both the women with overt diabetes and those with gestational diabetes, when compared with normal pregnant subjects, had a more prolonged prejection period (PEP) and a shorter left ventricular ejection time (LVET) and, consequently, a higher PEP/LVET ratio. Five weeks after delivery, abnormalities of systolic time intervals persisted in patients with clinical diabetes, but there were no differences at this time between patients with gestational diabetes and those in the control group. It is concluded that when a cardiac load is superimposed on patients who develop diabetes only under conditions of stress, as in pregnancy (gestational diabetes), abnormalities of myocardial function appear, which revert to normal when the stressful event is removed.
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M3 - Article
C2 - 6832177
AN - SCOPUS:0020681443
VL - 4
SP - 59
EP - 63
JO - European Heart Journal
JF - European Heart Journal
SN - 0195-668X
IS - 1
ER -