Reversible and irreversible structural modifications of erythrocyte membrane

C. Balduini, A. Brovelli, G. Pallavicini, F. Sinigaglia, G. Airoldi

Research output: Contribution to journalArticlepeer-review

Abstract

Membrane glycoprotein structure regulates the fate in the circulation of mammalian erythrocytes: the mechanism of this phenomenon was observed in rabbit and human red cells by in vivo and in vitro experiments. Glycoprotein remodeling can occur as a reversible desialylation process, produced by different events, or as an irreversible process consisting in a loss of sialoglycopeptides. The effect of these two phenomena on the viability of the red cell in the circulation was the subject of our investigation.

Original languageEnglish
Pages (from-to)401-408
Number of pages8
JournalActa Biologica et Medica Germanica
Volume40
Issue number4-5
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Medicine(all)

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