Reversible paresis of the left hand related to a migraine without aura attack

Ferdinando Maggioni, Federica Viaro, Renzo Manara, Valentina Citton, Giorgio Zanchin

Research output: Contribution to journalArticlepeer-review


Introduction: The comorbidity between migraine and stroke continues to be a debated topic. Prior cases of reversible neuroradiologic lesions have been described in migrainous patients and in particular for those suffering from migraine with aura or complicated migraine attacks. Case Report: We describe a patient that presented with a migraine without aura (MO) attack followed by paresis of the left hand that resolved completely within 4 days. An early brain magnetic resonance image (MRI) showed congruent cytotoxic-like alteration, whereas the lesion was no longer detectable on a standard 8-day MRI follow-up. A focused high-resolution MRI disclosed a very small cortical lesion, whereas a functional MRI demonstrated normal activation of the previously affected cortex at 8-month follow-up. Conclusions: This MO patient presented with an ischemic-like lesion associated with migraine that reversed completely on MRI examination suggesting that migrainous infarction can occur in MO. Focused highresolution sequences at follow-up might disclose subtle cortical lesions that could be more frequent than thought, coexisting with the wellknown white matter hyperintensities not associated with neurological signs.

Original languageEnglish
Pages (from-to)316-320
Number of pages5
Issue number5
Publication statusPublished - Sep 2012


  • fMRI
  • Functional MRI
  • Migraine without aura
  • MRI
  • Reversible ischemic lesion
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology


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