Review and perspectives on pharmacological vitreolysis

Francesco Bandello; Carlo La Spina; Lorenzo Iuliano; Giovanni Fogliato; Maurizio Battaglia Parodi

doi:10.1159/000354547

Review and perspectives on pharmacological vitreolysis

Francesco Bandello, Carlo La Spina, Lorenzo Iuliano, Giovanni Fogliato, Maurizio Battaglia Parodi

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

The vitreous is involved in multiple diseases when an incomplete posterior vitreous detachment (PVD) occurs. An incomplete PVD can lead to several pathological conditions. Such visually threatening conditions are traditionally of exclusive surgical interest. In contrast, pharmacological vitreolysis is the effort to reduce or eliminate the pathogenetic role of the vitreous solely by means of drug delivery. Here we aim to review and summarize the evidence available to date about this challenging new approach.

Original language	English
Pages (from-to)	179-185
Number of pages	7
Journal	Ophthalmologica
Volume	230
Issue number	4
DOIs	https://doi.org/10.1159/000354547
Publication status	Published - Nov 2013

Keywords

Ocriplasmin
Plasmin
Vitreolysis

ASJC Scopus subject areas

Ophthalmology
Sensory Systems

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10.1159/000354547

Cite this

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AU - Iuliano, Lorenzo

AU - Fogliato, Giovanni

AU - Parodi, Maurizio Battaglia

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AB - The vitreous is involved in multiple diseases when an incomplete posterior vitreous detachment (PVD) occurs. An incomplete PVD can lead to several pathological conditions. Such visually threatening conditions are traditionally of exclusive surgical interest. In contrast, pharmacological vitreolysis is the effort to reduce or eliminate the pathogenetic role of the vitreous solely by means of drug delivery. Here we aim to review and summarize the evidence available to date about this challenging new approach.

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Review and perspectives on pharmacological vitreolysis

Abstract

Keywords

ASJC Scopus subject areas

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