Rhabdomyosarcoma with primary osteolytic lesions simulating non-hodgkin's lymphoma

Franco Locatelli, Patrizia Tonani, Fulvio Porta, Marco Zecca, Giampiero Beluffi, Paola Fiori, Renato Rosso, Marco Paulli, Giuseppe Basso, Rosangela Invernizzi, Luigi Nespoli, Francesca Severi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We report the case of an 8-year-old child presenting with the pathological fracture of two vertebral bodies due to bone lytic lesions. Physical and instrumental examinations did not show any further evidence of disease. However, bone marrow aspirate showed an infiltrate of poorly differentiated cells. When the child was transferred to the Department of Pediatrics, lymphoblastic leukemia was suspected. Although the morphology of the bone marrow biopsy could have suggested a lymphoblastic lymphoma, further immunochemical and immunological studies together with the study of tissue surface antigens resulted in a diagnosis of embryonal rhabdomyosarcoma with an unusual presentation.

Original languageEnglish
Pages (from-to)159-164
Number of pages6
JournalPediatric Hematology and Oncology
Volume8
Issue number2
DOIs
Publication statusPublished - 1991

Fingerprint

Rhabdomyosarcoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Non-Hodgkin's Lymphoma
Bone
Bone Marrow
Embryonal Rhabdomyosarcoma
Spontaneous Fractures
Surface Antigens
Physical Examination
Pediatrics
Biopsy
Antigens
Bone and Bones
Tissue
Lymphoma

Keywords

  • Osteolytic lesions
  • Rhabdomyosarcoma
  • Soft-tissue tumors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology
  • Cancer Research
  • Management of Technology and Innovation

Cite this

Rhabdomyosarcoma with primary osteolytic lesions simulating non-hodgkin's lymphoma. / Locatelli, Franco; Tonani, Patrizia; Porta, Fulvio; Zecca, Marco; Beluffi, Giampiero; Fiori, Paola; Rosso, Renato; Paulli, Marco; Basso, Giuseppe; Invernizzi, Rosangela; Nespoli, Luigi; Severi, Francesca.

In: Pediatric Hematology and Oncology, Vol. 8, No. 2, 1991, p. 159-164.

Research output: Contribution to journalArticle

Locatelli, Franco ; Tonani, Patrizia ; Porta, Fulvio ; Zecca, Marco ; Beluffi, Giampiero ; Fiori, Paola ; Rosso, Renato ; Paulli, Marco ; Basso, Giuseppe ; Invernizzi, Rosangela ; Nespoli, Luigi ; Severi, Francesca. / Rhabdomyosarcoma with primary osteolytic lesions simulating non-hodgkin's lymphoma. In: Pediatric Hematology and Oncology. 1991 ; Vol. 8, No. 2. pp. 159-164.
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AU - Beluffi, Giampiero

AU - Fiori, Paola

AU - Rosso, Renato

AU - Paulli, Marco

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