Rheumatic diseases and autoimmune vascular dementia

F. Atzeni, N. Pipitone, L. Iaccarino, I.F. Masala, R. Weiss, A. Alciati, A. Doria, J. Chapmanand, P. Sarzi-Puttini

Research output: Contribution to journalArticlepeer-review


Vascular dementia (VD) comes second after Alzheimer's disease (AD) as a cause of impaired cognition. VD is not a specific nosological entity, but rather a syndrome encompassing a number of diseases caused by impaired supply of blood to the brain. Systemic autoimmune disorders such as systemic lupus erythematosus, rheumatoid arthritis, vasculitis and antiphospholipid syndrome (APS) can be associated with dementia. VD is often related to the presence of traditional cardiovascular risk factors, but it may also be associated with a host of disorders affecting the brain blood vessels, neuronal cells, or both. It is important to entertain in the differential diagnosis of VD, to recognize and to cure them accurately in order to preserve life's quality of our patients.
Autoimmunity; Central pain; Rheumatic diseases; Vascular dementia; Vasculitis
Original languageItalian
Pages (from-to)1265-1269
Number of pages5
JournalAutoimmunity Reviews
Issue number12
Publication statusPublished - 2017

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