Rheumatic disorders and primary biliary cirrhosis: An appraisal of 170 Italian patients

B. Marasini, M. Gagetta, V. Rossi, P. Ferrari

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Objective - To establish the frequency of connective tissue diseases (CTD) in a cohort of Italian patients with primary biliary cirrhosis (PBC) and to evaluate the availability of a marker for the early identification of the more common associated CTD. Methods - One hundred and seventy consecutive patients with histologically diagnosed PBC were screened for the presence of a CTD and/or Raynaud's phenomenon (RP). Patients were classified as having a CTD only if they fulfilled standardised criteria. Results - Forty seven patients had a CTD. The most common CTD was systemic sclerosis (SSc), found in 21 patients. RP was present in 54 patients, most of whom (n=39) had an associated CTD. The most prevalent autoantibodies included antinuclear antibodies (ANA) with anticentromere (ACA) and speckled patterns (34 and 33 patients, respectively) and extractable nuclear antigens (ENA, 27 patients). However, while the frequencies of ACA and ENA were significantly higher in patients with an associated CTD (p

Original languageEnglish
Pages (from-to)1046-1049
Number of pages4
JournalAnnals of the Rheumatic Diseases
Volume60
Issue number11
DOIs
Publication statusPublished - 2001

Fingerprint

Biliary Liver Cirrhosis
Connective Tissue Diseases
Tissue
Raynaud Disease
Nuclear Antigens
Antinuclear Antibodies
Systemic Scleroderma
Autoantibodies
Availability

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Rheumatic disorders and primary biliary cirrhosis : An appraisal of 170 Italian patients. / Marasini, B.; Gagetta, M.; Rossi, V.; Ferrari, P.

In: Annals of the Rheumatic Diseases, Vol. 60, No. 11, 2001, p. 1046-1049.

Research output: Contribution to journalArticle

Marasini, B. ; Gagetta, M. ; Rossi, V. ; Ferrari, P. / Rheumatic disorders and primary biliary cirrhosis : An appraisal of 170 Italian patients. In: Annals of the Rheumatic Diseases. 2001 ; Vol. 60, No. 11. pp. 1046-1049.
@article{7948583fc2ec43a88d1d9a49d0cb5c9a,
title = "Rheumatic disorders and primary biliary cirrhosis: An appraisal of 170 Italian patients",
abstract = "Objective - To establish the frequency of connective tissue diseases (CTD) in a cohort of Italian patients with primary biliary cirrhosis (PBC) and to evaluate the availability of a marker for the early identification of the more common associated CTD. Methods - One hundred and seventy consecutive patients with histologically diagnosed PBC were screened for the presence of a CTD and/or Raynaud's phenomenon (RP). Patients were classified as having a CTD only if they fulfilled standardised criteria. Results - Forty seven patients had a CTD. The most common CTD was systemic sclerosis (SSc), found in 21 patients. RP was present in 54 patients, most of whom (n=39) had an associated CTD. The most prevalent autoantibodies included antinuclear antibodies (ANA) with anticentromere (ACA) and speckled patterns (34 and 33 patients, respectively) and extractable nuclear antigens (ENA, 27 patients). However, while the frequencies of ACA and ENA were significantly higher in patients with an associated CTD (p",
author = "B. Marasini and M. Gagetta and V. Rossi and P. Ferrari",
year = "2001",
doi = "10.1136/ard.60.11.1046",
language = "English",
volume = "60",
pages = "1046--1049",
journal = "Annals of the Rheumatic Diseases",
issn = "0003-4967",
publisher = "BMJ Publishing Group",
number = "11",

}

TY - JOUR

T1 - Rheumatic disorders and primary biliary cirrhosis

T2 - An appraisal of 170 Italian patients

AU - Marasini, B.

AU - Gagetta, M.

AU - Rossi, V.

AU - Ferrari, P.

PY - 2001

Y1 - 2001

N2 - Objective - To establish the frequency of connective tissue diseases (CTD) in a cohort of Italian patients with primary biliary cirrhosis (PBC) and to evaluate the availability of a marker for the early identification of the more common associated CTD. Methods - One hundred and seventy consecutive patients with histologically diagnosed PBC were screened for the presence of a CTD and/or Raynaud's phenomenon (RP). Patients were classified as having a CTD only if they fulfilled standardised criteria. Results - Forty seven patients had a CTD. The most common CTD was systemic sclerosis (SSc), found in 21 patients. RP was present in 54 patients, most of whom (n=39) had an associated CTD. The most prevalent autoantibodies included antinuclear antibodies (ANA) with anticentromere (ACA) and speckled patterns (34 and 33 patients, respectively) and extractable nuclear antigens (ENA, 27 patients). However, while the frequencies of ACA and ENA were significantly higher in patients with an associated CTD (p

AB - Objective - To establish the frequency of connective tissue diseases (CTD) in a cohort of Italian patients with primary biliary cirrhosis (PBC) and to evaluate the availability of a marker for the early identification of the more common associated CTD. Methods - One hundred and seventy consecutive patients with histologically diagnosed PBC were screened for the presence of a CTD and/or Raynaud's phenomenon (RP). Patients were classified as having a CTD only if they fulfilled standardised criteria. Results - Forty seven patients had a CTD. The most common CTD was systemic sclerosis (SSc), found in 21 patients. RP was present in 54 patients, most of whom (n=39) had an associated CTD. The most prevalent autoantibodies included antinuclear antibodies (ANA) with anticentromere (ACA) and speckled patterns (34 and 33 patients, respectively) and extractable nuclear antigens (ENA, 27 patients). However, while the frequencies of ACA and ENA were significantly higher in patients with an associated CTD (p

UR - http://www.scopus.com/inward/record.url?scp=0034776921&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034776921&partnerID=8YFLogxK

U2 - 10.1136/ard.60.11.1046

DO - 10.1136/ard.60.11.1046

M3 - Article

C2 - 11602476

AN - SCOPUS:0034776921

VL - 60

SP - 1046

EP - 1049

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

SN - 0003-4967

IS - 11

ER -