Rheumatic manifestations in inflammatory bowel disease

Fabiola Atzeni, Caterina Defendenti, Maria Chiara Ditto, Alberto Batticciotto, Donatella Ventura, Marco Antivalle, Sandro Ardizzone, Piercarlo Sarzi-Puttini

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Musculoskeletal symptoms (articular, periarticular and muscular involvement, osteoporosis and related fractures, and fibromyalgia) are the most common frequent extra-intestinal manifestations of inflammatory bowel disease (IBD) and affect 6-46% of patients. IBD-related arthropathy is one of a group of inflammatory arthritides known as seronegative spondyloarthropathies (SpA), which also includes idiopathic ankylosing spondylitis (AS), reactive arthritis, psoriatic arthritis, and undifferentiated SpA.The articular involvement in IBD significantly affects the patients' quality of the life. Although magnetic resonance imaging (MRI) is still the gold standard for assessing entheseal involvement, ultrasonography (US) is a non-invasive and easily reproducible means of detecting early pathological changes in SpA patients. It can identify characteristic features of SpA such as enthesitis, bone erosions, synovitis, bursitis, and tenosynovitis and is therefore helpful for diagnostic purposes.Anti-TNF drugs should be used to treat AS patients with axial and peripheral symptoms (arthritis and enthesitis) who have persistently high levels of disease activity despite conventional treatment, and adalimumab and infliximab can also be beneficially used in patients with IBD.

Original languageEnglish
Pages (from-to)20-23
Number of pages4
JournalAutoimmunity Reviews
Volume13
Issue number1
DOIs
Publication statusPublished - Jan 2014

Fingerprint

Spondylarthropathies
Inflammatory Bowel Diseases
Ankylosing Spondylitis
Arthritis
Joints
Tenosynovitis
Bursitis
Reactive Arthritis
Psoriatic Arthritis
Synovitis
Fibromyalgia
Joint Diseases
Osteoporosis
Ultrasonography
Quality of Life
Magnetic Resonance Imaging
Bone and Bones
Pharmaceutical Preparations
Therapeutics

Keywords

  • Articular manifestations
  • Enthesitis
  • Inflammatory bowel disease
  • Ultrasonography

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Atzeni, F., Defendenti, C., Ditto, M. C., Batticciotto, A., Ventura, D., Antivalle, M., ... Sarzi-Puttini, P. (2014). Rheumatic manifestations in inflammatory bowel disease. Autoimmunity Reviews, 13(1), 20-23. https://doi.org/10.1016/j.autrev.2013.06.006

Rheumatic manifestations in inflammatory bowel disease. / Atzeni, Fabiola; Defendenti, Caterina; Ditto, Maria Chiara; Batticciotto, Alberto; Ventura, Donatella; Antivalle, Marco; Ardizzone, Sandro; Sarzi-Puttini, Piercarlo.

In: Autoimmunity Reviews, Vol. 13, No. 1, 01.2014, p. 20-23.

Research output: Contribution to journalArticle

Atzeni, F, Defendenti, C, Ditto, MC, Batticciotto, A, Ventura, D, Antivalle, M, Ardizzone, S & Sarzi-Puttini, P 2014, 'Rheumatic manifestations in inflammatory bowel disease', Autoimmunity Reviews, vol. 13, no. 1, pp. 20-23. https://doi.org/10.1016/j.autrev.2013.06.006
Atzeni F, Defendenti C, Ditto MC, Batticciotto A, Ventura D, Antivalle M et al. Rheumatic manifestations in inflammatory bowel disease. Autoimmunity Reviews. 2014 Jan;13(1):20-23. https://doi.org/10.1016/j.autrev.2013.06.006
Atzeni, Fabiola ; Defendenti, Caterina ; Ditto, Maria Chiara ; Batticciotto, Alberto ; Ventura, Donatella ; Antivalle, Marco ; Ardizzone, Sandro ; Sarzi-Puttini, Piercarlo. / Rheumatic manifestations in inflammatory bowel disease. In: Autoimmunity Reviews. 2014 ; Vol. 13, No. 1. pp. 20-23.
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