Rhino-cerebral zygomycosis after allogeneic transplant: Case report and literature review

Alina Tǎnase, Zsofia Varady, D. Coriu, Carmen Orban, Camellia Ghiţǎ, M. Grasu, A. Streinu Cercel, V. Del Bono

Research output: Contribution to journalArticlepeer-review

Abstract

The proportion of patients with hematological malignancies (HM) who develop rare invasive fungal infections (IFI) has increased worldwide over the past few decades. Zygomycosis is an opportunistic fungal infection, which begins in the nose and paranasal sinuses due to inhalation of fungal spores. Rhino-cerebral zygomycosis is the most common form of the disease, it typically develops in diabetic or immunocompromised patients and presents as an acute fulminate infection, which is often lethal. We report a case of rhino-cerebral zygomycosis in an allotransplanted patient to emphasize early diagnosis and treatment of this potentially fatal fungal infection. We discuss different risk factors, specific diagnosis procedures and review the current concepts in management of zygomycosis.

Original languageEnglish
Pages (from-to)715-718
Number of pages4
JournalRomanian Journal of Morphology and Embryology
Volume52
Issue number2
Publication statusPublished - 2011

Keywords

  • Allogeneic transplant
  • Mucormycosis
  • Rhino-cerebral
  • Zygomycosis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Embryology
  • Developmental Biology
  • Cell Biology

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