Right heart dysfunction: from pathophysiologic insights to therapeutic options: a translational overview

Valentina Mercurio; Alberto Palazzuoli; Michele Correale; Carlo Lombardi; Andrea Passantino; Alice Ravera; Gaetano Ruocco; Edoardo Sciatti; Marco Triggiani; Rocco Lagioia; Domenico Scrutinio; Carlo G Tocchetti; Savina Nodari

doi:10.2459/JCM.0000000000000700

Right heart dysfunction: from pathophysiologic insights to therapeutic options: a translational overview

Valentina Mercurio, Alberto Palazzuoli, Michele Correale, Carlo Lombardi, Andrea Passantino, Alice Ravera, Gaetano Ruocco, Edoardo Sciatti, Marco Triggiani, Rocco Lagioia, Domenico Scrutinio, Carlo G Tocchetti, Savina Nodari

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Contribution to journal › Review article › peer-review

Abstract

: The right ventricle has become increasingly studied in cardiovascular research. In this article, we describe specific pathophysiological characteristics of the right ventricle, with special focus on functional and molecular modifications as well as therapeutic strategies in right ventricular dysfunction, underlining the differences with the left ventricle. Then we analyze the main imaging modalities to assess right ventricular function in different clinical settings. Finally, we acknowledge main therapeutic advances for treatment of right heart diseases.

Original language	English
Pages (from-to)	613-623
Number of pages	11
Journal	Journal of cardiovascular medicine (Hagerstown, Md.)
Volume	19
Issue number	11
DOIs	https://doi.org/10.2459/JCM.0000000000000700
Publication status	Published - Nov 2018

Keywords

Animals
Cardiac Imaging Techniques
Heart Failure/diagnostic imaging
Hemodynamics
Humans
Multimodal Imaging
Predictive Value of Tests
Recovery of Function
Translational Medical Research
Treatment Outcome
Ventricular Dysfunction, Right/diagnostic imaging
Ventricular Function, Right
Ventricular Remodeling

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10.2459/JCM.0000000000000700

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Mercurio, V., Palazzuoli, A., Correale, M., Lombardi, C., Passantino, A., Ravera, A., Ruocco, G., Sciatti, E., Triggiani, M., Lagioia, R., Scrutinio, D., Tocchetti, C. G., & Nodari, S. (2018). Right heart dysfunction: from pathophysiologic insights to therapeutic options: a translational overview. Journal of cardiovascular medicine (Hagerstown, Md.), 19(11), 613-623. https://doi.org/10.2459/JCM.0000000000000700

Right heart dysfunction : from pathophysiologic insights to therapeutic options: a translational overview. / Mercurio, Valentina; Palazzuoli, Alberto; Correale, Michele; Lombardi, Carlo; Passantino, Andrea; Ravera, Alice; Ruocco, Gaetano; Sciatti, Edoardo; Triggiani, Marco; Lagioia, Rocco; Scrutinio, Domenico; Tocchetti, Carlo G; Nodari, Savina.

In: Journal of cardiovascular medicine (Hagerstown, Md.), Vol. 19, No. 11, 11.2018, p. 613-623.

Research output: Contribution to journal › Review article › peer-review

Mercurio, V, Palazzuoli, A, Correale, M, Lombardi, C, Passantino, A, Ravera, A, Ruocco, G, Sciatti, E, Triggiani, M, Lagioia, R, Scrutinio, D, Tocchetti, CG & Nodari, S 2018, 'Right heart dysfunction: from pathophysiologic insights to therapeutic options: a translational overview', Journal of cardiovascular medicine (Hagerstown, Md.), vol. 19, no. 11, pp. 613-623. https://doi.org/10.2459/JCM.0000000000000700

Mercurio, Valentina ; Palazzuoli, Alberto ; Correale, Michele ; Lombardi, Carlo ; Passantino, Andrea ; Ravera, Alice ; Ruocco, Gaetano ; Sciatti, Edoardo ; Triggiani, Marco ; Lagioia, Rocco ; Scrutinio, Domenico ; Tocchetti, Carlo G ; Nodari, Savina. / Right heart dysfunction : from pathophysiologic insights to therapeutic options: a translational overview. In: Journal of cardiovascular medicine (Hagerstown, Md.). 2018 ; Vol. 19, No. 11. pp. 613-623.

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