Right heart dysfunction: from pathophysiologic insights to therapeutic options: a translational overview

Valentina Mercurio, Alberto Palazzuoli, Michele Correale, Carlo Lombardi, Andrea Passantino, Alice Ravera, Gaetano Ruocco, Edoardo Sciatti, Marco Triggiani, Rocco Lagioia, Domenico Scrutinio, Carlo G Tocchetti, Savina Nodari

Research output: Contribution to journalReview articlepeer-review

Abstract

: The right ventricle has become increasingly studied in cardiovascular research. In this article, we describe specific pathophysiological characteristics of the right ventricle, with special focus on functional and molecular modifications as well as therapeutic strategies in right ventricular dysfunction, underlining the differences with the left ventricle. Then we analyze the main imaging modalities to assess right ventricular function in different clinical settings. Finally, we acknowledge main therapeutic advances for treatment of right heart diseases.

Original languageEnglish
Pages (from-to)613-623
Number of pages11
JournalJournal of cardiovascular medicine (Hagerstown, Md.)
Volume19
Issue number11
DOIs
Publication statusPublished - Nov 2018

Keywords

  • Animals
  • Cardiac Imaging Techniques
  • Heart Failure/diagnostic imaging
  • Hemodynamics
  • Humans
  • Multimodal Imaging
  • Predictive Value of Tests
  • Recovery of Function
  • Translational Medical Research
  • Treatment Outcome
  • Ventricular Dysfunction, Right/diagnostic imaging
  • Ventricular Function, Right
  • Ventricular Remodeling

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