Rigid-body transformation of list-mode projection data for respiratory motion correction in cardiac PET

L. Livieratos, L. Stegger, P. M. Bloomfield, K. Schafers, D. L. Bailey, P. G. Camici

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Respiratory motion is a source of artefacts and quantification errors in cardiac imaging. Preliminary studies with retrospective respiratory gating in PET support the observation of other imaging modalities of a rigid-body motion of the heart during respiration. However, the use of gating techniques to eliminate motion may result in poor count statistics per reconstructed image. We have implemented a motion correction technique which applies rigid-body transformations on list-mode data event-by-event on the basis of a geometric model of intersection of the lines-of-response with the scanner. Pre-correction for detector efficiencies and photon attenuation before transformation are included in the process. Projection data are acquired together with physiological signal (every ms) from an inductive respiration monitor with an elasticked belt at chest level. Data are retrospectively sorted into separate respiratory gates on an off-line workstation. Transformation parameters relating the gated images, estimated by means of image registration, can be applied on the original list-mode data to obtain a single motion-corrected dataset. The accuracy of the technique was assessed with point source data and a good correlation between applied and measured transformations, estimated from the centroid of the source, was observed. The technique was applied on phantom data with simulated respiratory motion and on patient data with C15O and 18FDG. Quantitative assessment of preliminary C15O patient datasets showed at least 4.5% improvement in the recovery coefficient at the centre of the left ventricle.

Original languageEnglish
Title of host publicationIEEE Nuclear Science Symposium Conference Record
EditorsS.D. Metzler
Pages2183-2187
Number of pages5
Volume3
Publication statusPublished - 2003
Event2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference - Portland, OR, United States
Duration: Oct 19 2003Oct 25 2003

Other

Other2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference
CountryUnited States
CityPortland, OR
Period10/19/0310/25/03

Keywords

  • Cardiovascular system
  • Motion compensation
  • Positron emission tomography
  • Respiratory system

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

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