Risk factors and acute ischemic stroke subtypes

Aliaksei Kisialiou, Rodolfo Grella, Albino Carrizzo, Giordana Pelone, Michelangelo Bartolo, Chiara Zucchella, Francesco Rozza, Giovanni Grillea, Claudio Colonnese, Luigi Formisano, Maria Lembo, Annibale A. Puca, Carmine Vecchione

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background Acute ischemic stroke (AIS) is influenced by gender, age, and the brain site affected. Better characterization of AIS is necessary for improving guidelines, prevention, and destination of resources. Methods Demographics, prestroke conditions, etiology, subtypes, specific hospital outcome, clinical and laboratory parameters, and mortality rates were prospectively registered in 105 southern Italian patients. Results AIS became more frequent in women than in men after age 65 years. Cryptogenic AIS decreased with age independently of sex and lesion site. Cerebellum-brainstem stroke was more prevalent in men, whereas anterior AIS was more frequent in women. There were no overall differences in 6- and 12-month survival rates based on site or sex; however, mortality rates were high after age 80 years. Chronic kidney disease was more frequent in patients with cerebellum-brainstem stroke, and its prevalence increased significantly with age independently of sex. Association of AIS with arterial hypertension, diabetes, and previous myocardial infarction increased with age, whereas that with active smoking decreased with age, independently of sex and site. Conclusion Specific AIS etiology and blood characteristics associated independently to the youngest and oldest AIS patients, respectively. Chronic kidney disease was a specific predictor of cerebellum-brainstem AIS. AIS mortality showed peculiar association with the oldest patients.

Original languageEnglish
Pages (from-to)41-46
Number of pages6
JournalJournal of the Neurological Sciences
Volume339
Issue number1-2
DOIs
Publication statusPublished - Apr 15 2014

Fingerprint

Stroke
Brain Stem Infarctions
Cerebellum
Chronic Renal Insufficiency
Mortality
Brain Stem
Survival Rate
Smoking
Myocardial Infarction
Demography
Guidelines
Hypertension
Brain

Keywords

  • Cohort study
  • Epidemiology
  • Men
  • Risk factors
  • Stroke
  • Women

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Risk factors and acute ischemic stroke subtypes. / Kisialiou, Aliaksei; Grella, Rodolfo; Carrizzo, Albino; Pelone, Giordana; Bartolo, Michelangelo; Zucchella, Chiara; Rozza, Francesco; Grillea, Giovanni; Colonnese, Claudio; Formisano, Luigi; Lembo, Maria; Puca, Annibale A.; Vecchione, Carmine.

In: Journal of the Neurological Sciences, Vol. 339, No. 1-2, 15.04.2014, p. 41-46.

Research output: Contribution to journalArticle

Kisialiou, A, Grella, R, Carrizzo, A, Pelone, G, Bartolo, M, Zucchella, C, Rozza, F, Grillea, G, Colonnese, C, Formisano, L, Lembo, M, Puca, AA & Vecchione, C 2014, 'Risk factors and acute ischemic stroke subtypes', Journal of the Neurological Sciences, vol. 339, no. 1-2, pp. 41-46. https://doi.org/10.1016/j.jns.2014.01.014
Kisialiou A, Grella R, Carrizzo A, Pelone G, Bartolo M, Zucchella C et al. Risk factors and acute ischemic stroke subtypes. Journal of the Neurological Sciences. 2014 Apr 15;339(1-2):41-46. https://doi.org/10.1016/j.jns.2014.01.014
Kisialiou, Aliaksei ; Grella, Rodolfo ; Carrizzo, Albino ; Pelone, Giordana ; Bartolo, Michelangelo ; Zucchella, Chiara ; Rozza, Francesco ; Grillea, Giovanni ; Colonnese, Claudio ; Formisano, Luigi ; Lembo, Maria ; Puca, Annibale A. ; Vecchione, Carmine. / Risk factors and acute ischemic stroke subtypes. In: Journal of the Neurological Sciences. 2014 ; Vol. 339, No. 1-2. pp. 41-46.
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