The benefits of estrogen replacement therapy are well established in the relief of menopausal symptoms but longer term benefits of a great reduction in ischaemic heart and cardiovascular diseases are of greater impact epidemiologically. However controversy still surrounds the possible risk association that such treatment may have on endocrine sensitive tissues such as the breast and endometrium. The 50% reduction in cardiovascular disease and osteoporotic hip fractures, the most common cause of morbidity and mortality in the elderly, due to long term HRT would outweigh any other known risks and even a doubling of the risk of breast cancer would not seriously compromise this benefit.
|Number of pages||5|
|Journal||Giornale di Gerontologia|
|Publication status||Published - 1993|
ASJC Scopus subject areas
- Geriatrics and Gerontology