Risk factors for adenocarcinoma of the small intestine

Eva Negri, Cristina Bosetti, Carlo La Vecchia, Francesca Fioretti, Ettore Conti, Silvia Franceschi

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

We have investigated the relation between alcohol, tobacco and dietary habits and risk of adenocarcinoma of the small intestine using data from 2 hospital-based case-control studies on intestinal cancers conducted in 6 Italian centres between 1985 and 1996. Cases were 23 patients below age 75 years with adenocarcinoma of the small intestine. Controls were 230 patients admitted to hospital for a wide spectrum of acute, non-neoplastic, non- digestive tract diseases, matched to cases on sex, age, study and centre. Odds ratios (ORs) were estimated using conditional logistic regression. Alcohol and tobacco consumption did not increase the risk of adenocarcinoma of the small intestine. The risk appeared to be directly related to intake of bread, pasta or rice (OR = 3.8), sugar (OR = 2.9) and red meat (OR = 4.6), and inversely to coffee (OR = 0.4), fish (OR = 0.3), vegetables (OR = 0.3) and fruit (OR = 0.6). Our results suggest that dietary correlates of adenocarcinoma of the small intestine are similar to those of colon cancer and at least of the same magnitude. While the present data are inconsistent with a major effect of tobacco or alcohol, a moderate association between these factors and small bowel cancer may have been obscured by the play of chance.

Original languageEnglish
Pages (from-to)171-174
Number of pages4
JournalInternational Journal of Cancer
Volume82
Issue number2
DOIs
Publication statusPublished - 1999

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Small Intestine
Adenocarcinoma
Odds Ratio
Intestinal Neoplasms
Tobacco
Alcohols
Bread
Coffee
Tobacco Use
Feeding Behavior
Alcohol Drinking
Vegetables
Colonic Neoplasms
Gastrointestinal Tract
Case-Control Studies
Fruit
Fishes
Logistic Models

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Risk factors for adenocarcinoma of the small intestine. / Negri, Eva; Bosetti, Cristina; La Vecchia, Carlo; Fioretti, Francesca; Conti, Ettore; Franceschi, Silvia.

In: International Journal of Cancer, Vol. 82, No. 2, 1999, p. 171-174.

Research output: Contribution to journalArticle

Negri, Eva ; Bosetti, Cristina ; La Vecchia, Carlo ; Fioretti, Francesca ; Conti, Ettore ; Franceschi, Silvia. / Risk factors for adenocarcinoma of the small intestine. In: International Journal of Cancer. 1999 ; Vol. 82, No. 2. pp. 171-174.
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