Risk factors for HIV infection in drug addicts from the Northeast of Italy

S. Franceschi, U. Tirelli, E. Vaccher, D. Serraino, M. Crovatto, P. De Paoli, S. Diodato, C. La Vecchia, A. Decarli, S. Monfardini

Research output: Contribution to journalArticle

Abstract

Prevalence and determinants of HIV infection were assessed in 313 parenteral drug addicts admitted to five Centers for Drug-Addict Assistance and two prisons located in the northeast of Italy (Friuli Venezia-Giulia), an area at some distance from the major Italian cities first reached by the AIDS epidemic. The overall prevalence of HIV positivity was also rather high in this area, ie 30% with 24-36% confidence interval. The most important risk factors (besides syringe sharing applicable to all drug addicts), turned out to be of a geographical nature, ie living in Pordenone provine (where a US military base is located) or coming from other endemic areas and having travelled long distances in the past three years. Prostitution also seemed to increase the risk of infection, but duration of drug addiction had little effect. In addition to persistent generalized lymphadenopathy (closely linked to HIV infection), reversal of helper:suppressor T-cell ratio was found in 67% of HIV positive individuals, but also in 31% of HIV negative ones. Clinical signs and symptoms strongly linked with HIV positivity were fatigue, weight loss, splenomegaly, fever and nocturnal sweats.

Original languageEnglish
Pages (from-to)162-167
Number of pages6
JournalInternational Journal of Epidemiology
Volume17
Issue number1
Publication statusPublished - 1988

Fingerprint

HIV Infection
Risk Factors
Drug Users
Italy
HIV Infections
Drugs
Military bases
HIV
Prisons
Syringes
T-cells
Positivity
Military Facilities
Fatigue of materials
Needle Sharing
Sex Work
Sweat
Splenomegaly
Helper-Inducer T-Lymphocytes
Reversal

ASJC Scopus subject areas

  • Epidemiology
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Reproductive Medicine
  • Obstetrics and Gynaecology

Cite this

Franceschi, S., Tirelli, U., Vaccher, E., Serraino, D., Crovatto, M., De Paoli, P., ... Monfardini, S. (1988). Risk factors for HIV infection in drug addicts from the Northeast of Italy. International Journal of Epidemiology, 17(1), 162-167.

Risk factors for HIV infection in drug addicts from the Northeast of Italy. / Franceschi, S.; Tirelli, U.; Vaccher, E.; Serraino, D.; Crovatto, M.; De Paoli, P.; Diodato, S.; La Vecchia, C.; Decarli, A.; Monfardini, S.

In: International Journal of Epidemiology, Vol. 17, No. 1, 1988, p. 162-167.

Research output: Contribution to journalArticle

Franceschi, S, Tirelli, U, Vaccher, E, Serraino, D, Crovatto, M, De Paoli, P, Diodato, S, La Vecchia, C, Decarli, A & Monfardini, S 1988, 'Risk factors for HIV infection in drug addicts from the Northeast of Italy', International Journal of Epidemiology, vol. 17, no. 1, pp. 162-167.
Franceschi, S. ; Tirelli, U. ; Vaccher, E. ; Serraino, D. ; Crovatto, M. ; De Paoli, P. ; Diodato, S. ; La Vecchia, C. ; Decarli, A. ; Monfardini, S. / Risk factors for HIV infection in drug addicts from the Northeast of Italy. In: International Journal of Epidemiology. 1988 ; Vol. 17, No. 1. pp. 162-167.
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