Risk factors for local recurrence following lateral neck dissection for papillary thyroid carcinoma

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Abstract

Purpose: We aimed to evaluate risk factors for local recurrence following lateral neck dissection (LND) for papillary thyroid carcinoma (PTC). Methods: Two hundred and nine patients who underwent therapeutic primary or reoperative LND for PTC were included. Results: One hundred eighty-one patients underwent primary LND at our Institution, the remaining 28 were referred for recurrence following LND outside the Institution. Comparing patients who required reoperation for recurrent lateral neck disease with those who did not recur, no significant difference was found concerning sex, tumor size, multifocal disease, extracapsular invasion, histological variant, pT stage (P = NS). At univariate analysis, age, mean number of removed lateral neck nodes at first operation, the extent of initial LND and surgery performed outside the Institution were risk factors for recurrence (P < 0.001). Conclusions: Limited LND and surgery performed at non referral Centers were non tumor-related risk factors for recurrence following therapeutic LND for PTC.

Original languageEnglish
JournalEndocrine
DOIs
Publication statusAccepted/In press - Jan 1 2018

Fingerprint

Neck Dissection
Recurrence
Neck
Papillary Thyroid cancer
Reoperation
Neoplasms
Referral and Consultation
Therapeutics

Keywords

  • Lateral neck dissection
  • Lymph node metastases
  • Papillary thyroid carcinoma
  • Recurrence of papillary thyroid carcinoma
  • Reoperative lateral neck dissection

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

@article{77250a1942cf4abb8dc99cddb3f5f53c,
title = "Risk factors for local recurrence following lateral neck dissection for papillary thyroid carcinoma",
abstract = "Purpose: We aimed to evaluate risk factors for local recurrence following lateral neck dissection (LND) for papillary thyroid carcinoma (PTC). Methods: Two hundred and nine patients who underwent therapeutic primary or reoperative LND for PTC were included. Results: One hundred eighty-one patients underwent primary LND at our Institution, the remaining 28 were referred for recurrence following LND outside the Institution. Comparing patients who required reoperation for recurrent lateral neck disease with those who did not recur, no significant difference was found concerning sex, tumor size, multifocal disease, extracapsular invasion, histological variant, pT stage (P = NS). At univariate analysis, age, mean number of removed lateral neck nodes at first operation, the extent of initial LND and surgery performed outside the Institution were risk factors for recurrence (P < 0.001). Conclusions: Limited LND and surgery performed at non referral Centers were non tumor-related risk factors for recurrence following therapeutic LND for PTC.",
keywords = "Lateral neck dissection, Lymph node metastases, Papillary thyroid carcinoma, Recurrence of papillary thyroid carcinoma, Reoperative lateral neck dissection",
author = "Marco Raffaelli and {De Crea}, Carmela and Luca Sessa and Tempera, {Serena Elisa} and Amanda Belluzzi and Lombardi, {Celestino P.} and Rocco Bellantone",
year = "2018",
month = "1",
day = "1",
doi = "10.1007/s12020-018-1788-9",
language = "English",
journal = "Endocrine",
issn = "1355-008X",
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T1 - Risk factors for local recurrence following lateral neck dissection for papillary thyroid carcinoma

AU - Raffaelli, Marco

AU - De Crea, Carmela

AU - Sessa, Luca

AU - Tempera, Serena Elisa

AU - Belluzzi, Amanda

AU - Lombardi, Celestino P.

AU - Bellantone, Rocco

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Purpose: We aimed to evaluate risk factors for local recurrence following lateral neck dissection (LND) for papillary thyroid carcinoma (PTC). Methods: Two hundred and nine patients who underwent therapeutic primary or reoperative LND for PTC were included. Results: One hundred eighty-one patients underwent primary LND at our Institution, the remaining 28 were referred for recurrence following LND outside the Institution. Comparing patients who required reoperation for recurrent lateral neck disease with those who did not recur, no significant difference was found concerning sex, tumor size, multifocal disease, extracapsular invasion, histological variant, pT stage (P = NS). At univariate analysis, age, mean number of removed lateral neck nodes at first operation, the extent of initial LND and surgery performed outside the Institution were risk factors for recurrence (P < 0.001). Conclusions: Limited LND and surgery performed at non referral Centers were non tumor-related risk factors for recurrence following therapeutic LND for PTC.

AB - Purpose: We aimed to evaluate risk factors for local recurrence following lateral neck dissection (LND) for papillary thyroid carcinoma (PTC). Methods: Two hundred and nine patients who underwent therapeutic primary or reoperative LND for PTC were included. Results: One hundred eighty-one patients underwent primary LND at our Institution, the remaining 28 were referred for recurrence following LND outside the Institution. Comparing patients who required reoperation for recurrent lateral neck disease with those who did not recur, no significant difference was found concerning sex, tumor size, multifocal disease, extracapsular invasion, histological variant, pT stage (P = NS). At univariate analysis, age, mean number of removed lateral neck nodes at first operation, the extent of initial LND and surgery performed outside the Institution were risk factors for recurrence (P < 0.001). Conclusions: Limited LND and surgery performed at non referral Centers were non tumor-related risk factors for recurrence following therapeutic LND for PTC.

KW - Lateral neck dissection

KW - Lymph node metastases

KW - Papillary thyroid carcinoma

KW - Recurrence of papillary thyroid carcinoma

KW - Reoperative lateral neck dissection

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