TY - JOUR
T1 - Risk factors for pelvic endometriosis in women with pelvic pain or infertility
AU - Parazzini, Fabio
AU - Ardovino, Italo
AU - Struzziero, Elisario
AU - Zanardi, Ettore
AU - Pungetti, Daniela
AU - Mais, Valerio
AU - Ajossa, Silvio
AU - Mignemi, Giovanni
AU - Di Leo, Luciano
AU - Bianchi, Albino
AU - Campobasso, Carlo
AU - Scarselli, Gian Franco
AU - Bracco, Gianluca
AU - Capetta, Piero
AU - Bertulessi, Carlo
AU - Moroni, Simona
AU - Mazza, Patrizia
AU - Vercellini, Paolo
AU - Crosignani, Pier Giorgio
AU - Modena, Alfio Bacchi
AU - Casa, Alessandro
AU - Massobrio, Marco
AU - Ansaldi, Cristina
AU - Trossarelli, Gian Franco
AU - Gervasi, Maria Teresa
AU - Marsoni, Vittorio
AU - Guaschino, Secondo
AU - Troiano, Luigi
AU - Ricci, Giuseppe
AU - Beretta, Paolo
AU - Franchi, Massimo
PY - 1999/4/1
Y1 - 1999/4/1
N2 - Objective: The objective of the study was to analyse the relationship between selected characteristics and risk of pelvic endometriosis. Study design: Eligible for the study were 817 women with primary or secondary infertility or pelvic pain requiring laparoscopy. Of these, 393 were included for infertility and 424 for pelvic pain. Results: A total of 345 (42.2%) had a diagnosis of endometriosis and 472 did not have the disease. Multiparous women had endomertriosos less frequently than nulliparous, the estimated odds ratios (OR) were respectively 0.9 (95% confidence interval, CI, 0.5-1.6) and 0.4 (95% CI 0.2-0.7) in women reporting one and two or more births. In comparison with women reporting no spontaneous abortion, the estimated OR was 0.3 (95% CI 0.2-0.5) in those who reported ≥1 miscarriage. In comparison with women reporting menstrual cycles lasting ≥25 days subjects with totally irregular menstrual cycles had a reduced risk of endometriosis (OR 0.6, 95% CI 0.3-0.9). No significant association emerged between smoking, age at menarche and risk of endometriosis. Conclusions: this study confirms, with a different methodological approach to previously published studies, that multiparity, a history of abortion and lifelong irregular menstrual pattern decrease the risk of endometriosis in women with pelvic pain and infertility. Copyright (C) 1999 Elsevier Science Ireland Ltd.
AB - Objective: The objective of the study was to analyse the relationship between selected characteristics and risk of pelvic endometriosis. Study design: Eligible for the study were 817 women with primary or secondary infertility or pelvic pain requiring laparoscopy. Of these, 393 were included for infertility and 424 for pelvic pain. Results: A total of 345 (42.2%) had a diagnosis of endometriosis and 472 did not have the disease. Multiparous women had endomertriosos less frequently than nulliparous, the estimated odds ratios (OR) were respectively 0.9 (95% confidence interval, CI, 0.5-1.6) and 0.4 (95% CI 0.2-0.7) in women reporting one and two or more births. In comparison with women reporting no spontaneous abortion, the estimated OR was 0.3 (95% CI 0.2-0.5) in those who reported ≥1 miscarriage. In comparison with women reporting menstrual cycles lasting ≥25 days subjects with totally irregular menstrual cycles had a reduced risk of endometriosis (OR 0.6, 95% CI 0.3-0.9). No significant association emerged between smoking, age at menarche and risk of endometriosis. Conclusions: this study confirms, with a different methodological approach to previously published studies, that multiparity, a history of abortion and lifelong irregular menstrual pattern decrease the risk of endometriosis in women with pelvic pain and infertility. Copyright (C) 1999 Elsevier Science Ireland Ltd.
KW - Endometriosis
KW - Menstrual characteristics
KW - Reproductive factors
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=0032935922&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032935922&partnerID=8YFLogxK
U2 - 10.1016/S0301-2115(98)00332-7
DO - 10.1016/S0301-2115(98)00332-7
M3 - Article
C2 - 10391532
AN - SCOPUS:0032935922
VL - 83
SP - 195
EP - 199
JO - European Journal of Obstetrics, Gynecology and Reproductive Biology
JF - European Journal of Obstetrics, Gynecology and Reproductive Biology
SN - 0028-2243
IS - 2
ER -