Risk factors for recurrent syncope and subsequent fatal or near-fatal events in children and adolescents with long QT syndrome

Judy F. Liu, Christian Jons, Arthur J. Moss, Scott McNitt, Derick R. Peterson, Ming Qi, Wojciech Zareba, Jennifer L. Robinson, Alon Barsheshet, Michael J. Ackerman, Jesaia Benhorin, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, Silvia G. Priori, Peter J. Schwartz, Jeffrey Towbin, Michael Vincent, Li Zhang, Ilan Goldenberg

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: We aimed to identify risk factors for recurrent syncope in children and adolescents with congenital long QT syndrome (LQTS). Background: Data regarding risk assessment in LQTS after the occurrence of the first syncope episode are limited. Methods: The Prentice-Williams-Peterson conditional gap time model was used to identify risk factors for recurrent syncope from birth through age 20 years among 1,648 patients from the International Long QT Syndrome Registry. Results: Multivariate analysis demonstrated that corrected QT interval (QTc) duration (

Original languageEnglish
Pages (from-to)941-950
Number of pages10
JournalJournal of the American College of Cardiology
Volume57
Issue number8
DOIs
Publication statusPublished - Feb 22 2011

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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