Abstract
100 women underwent wide resection for palpable or mammographically detected breast lesions (1 woman had bilateral lesions). Histology excluded invasive cancer, but one or more foci of lobular carcinoma in situ (LCIS) were observed. There have been no recurrences in the 20 women who underwent total mastectomy. In the 12 patients who had a subsequent wide excision and the 68 who received no other treatment 5 presented with an invasive cancer in the same breast at some distance from the LCIS site (median follow-up 58 months). The (observed/expected) rate per 1000 per year is 10.3 for an untreated LCIS. LCIS is therefore a risk factor for invasive carcinoma. Nevertheless this risk does not indicate the use of mutilating procedures and a wait-and-see policy is appropriate.
| Original language | English |
|---|---|
| Pages (from-to) | 35-37 |
| Number of pages | 3 |
| Journal | European Journal of Cancer and Clinical Oncology |
| Volume | 27 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1991 |
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ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Risk of invasive cancer in women with lobular carcinoma in situ of the breast. / Salvadori, Bruno; Bartoli, Cesare; Zurrida, Stefano; Delledonne, Vincenzo; Squicciarini, Paolo; Rovini, Dario; Barletta, Lucilla.
In: European Journal of Cancer and Clinical Oncology, Vol. 27, No. 1, 1991, p. 35-37.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Risk of invasive cancer in women with lobular carcinoma in situ of the breast
AU - Salvadori, Bruno
AU - Bartoli, Cesare
AU - Zurrida, Stefano
AU - Delledonne, Vincenzo
AU - Squicciarini, Paolo
AU - Rovini, Dario
AU - Barletta, Lucilla
PY - 1991
Y1 - 1991
N2 - 100 women underwent wide resection for palpable or mammographically detected breast lesions (1 woman had bilateral lesions). Histology excluded invasive cancer, but one or more foci of lobular carcinoma in situ (LCIS) were observed. There have been no recurrences in the 20 women who underwent total mastectomy. In the 12 patients who had a subsequent wide excision and the 68 who received no other treatment 5 presented with an invasive cancer in the same breast at some distance from the LCIS site (median follow-up 58 months). The (observed/expected) rate per 1000 per year is 10.3 for an untreated LCIS. LCIS is therefore a risk factor for invasive carcinoma. Nevertheless this risk does not indicate the use of mutilating procedures and a wait-and-see policy is appropriate.
AB - 100 women underwent wide resection for palpable or mammographically detected breast lesions (1 woman had bilateral lesions). Histology excluded invasive cancer, but one or more foci of lobular carcinoma in situ (LCIS) were observed. There have been no recurrences in the 20 women who underwent total mastectomy. In the 12 patients who had a subsequent wide excision and the 68 who received no other treatment 5 presented with an invasive cancer in the same breast at some distance from the LCIS site (median follow-up 58 months). The (observed/expected) rate per 1000 per year is 10.3 for an untreated LCIS. LCIS is therefore a risk factor for invasive carcinoma. Nevertheless this risk does not indicate the use of mutilating procedures and a wait-and-see policy is appropriate.
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UR - http://www.scopus.com/inward/citedby.url?scp=0025973923&partnerID=8YFLogxK
U2 - 10.1016/0277-5379(91)90055-I
DO - 10.1016/0277-5379(91)90055-I
M3 - Article
VL - 27
SP - 35
EP - 37
JO - European Journal of Cancer
JF - European Journal of Cancer
SN - 0959-8049
IS - 1
ER -