Risk of leukaemia and residential exposure to air pollution in an industrial area in Northern Italy: A case-control study

Stefano Parodi, Irene Santi, Claudia Casella, Antonella Puppo, Fabio Montanaro, Vincenzo Fontana, Massimiliano Pescetto, Emanuele Stagnaro

Research output: Contribution to journalArticle

Abstract

Leukaemia risk in adult populations exposed to environmental air pollution is poorly investigated. We have carried out a population-based case-control study in an area that included a fossil fuel power plant, a coke oven and two big chemical industries. Information on residential history and several risk factors for leukaemia was obtained from 164 cases, diagnosed between 2002 and 2005, and 279 controls. A higher risk for subjects residing in polluted areas was observed, but statistical significance was not reached (adjusted OR = 1.11 and 1.56 for subjects living in moderately and in heavily polluted zones, respectively, p = 0.190). Results suggest a possible aetiological role of residential air pollution from industrial sites on the risk of developing leukaemia in adult populations. However, the proportion of eligible subjects excluded from the study and the lack of any measure of air pollution prevent definitive conclusions from being drawn.

Original languageEnglish
Pages (from-to)393-404
Number of pages12
JournalInternational Journal of Environmental Health Research
Volume25
Issue number4
DOIs
Publication statusPublished - Jul 4 2015

Keywords

  • air pollution
  • case-control study
  • environmental risk
  • industrial pollution
  • leukaemia

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Pollution
  • Public Health, Environmental and Occupational Health

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