Risk scores to facilitate preoperative prediction of transfusion and large volume blood transfusion associated with adult cardiac surgery

R. Goudie, J. A C Sterne, V. Verheyden, M. Bhabra, M. Ranucci, G. J. Murphy

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The aim of this study was to develop two novel risk prediction scores for transfusion and bleeding that would be used to inform treatment decisions, quality assurance, and clinical trial design in cardiac surgery. Methods: Clinical data prospectively collected from 26 UK cardiac surgical centres and a single European centre were used to develop two risk prediction models: one for any red blood cell (RBC) transfusion, and the other for large volume blood transfusion (≥4 RBC units; LVBT), an index of severe blood loss. 'Complete case' data were available for 24 749 patients. Multiple imputation was used for missing covariate data (typically

Original languageEnglish
Pages (from-to)757-766
Number of pages10
JournalBritish Journal of Anaesthesia
Volume114
Issue number5
DOIs
Publication statusPublished - May 1 2015

Keywords

  • blood transfusion
  • cardiac anaesthesia

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Medicine(all)

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