Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy

Karen Sliwa, Peter van der Meer, Mark C. Petrie, Alexandra Frogoudaki, Mark R. Johnson, Denise Hilfiker-Kleiner, Righab Hamdan, Alice M. Jackson, Bassem Ibrahim, Amam Mbakwem, Carsten Tschöpe, Vera Regitz-Zagrosek, Elmir Omerovic, Jolien Roos-Hesselink, Michael Gatzoulis, Oktay Tutarel, Susanna Price, Stephane Heymans, Andrew J.S. Coats, Christian MüllerOvidiu Chioncel, Thomas Thum, Rudolf A. de Boer, Ewa Jankowska, Piotr Ponikowski, Alexander R. Lyon, Guiseppe Rosano, Petar M. Seferovic, Johann Bauersachs

Research output: Contribution to journalArticlepeer-review

Abstract

This position paper focusses on the pathophysiology, diagnosis and management of women diagnosed with a cardiomyopathy, or at risk of heart failure (HF), who are planning to conceive or present with (de novo or previously unknown) HF during or after pregnancy. This includes the heterogeneous group of heart muscle diseases such as hypertrophic, dilated, arrhythmogenic right ventricular and non-classified cardiomyopathies, left ventricular non-compaction, peripartum cardiomyopathy, Takotsubo syndrome, adult congenital heart disease with HF, and patients with right HF. Also, patients with a history of chemo-/radiotherapy for cancer or haematological malignancies need specific pre-, during and post-pregnancy assessment and counselling. We summarize the current knowledge about pathophysiological mechanisms, including gene mutations, clinical presentation, diagnosis, and medical and device management, as well as risk stratification. Women with a known diagnosis of a cardiomyopathy will often require continuation of drug therapy, which has the potential to exert negative effects on the foetus. This position paper assists in balancing benefits and detrimental effects.

Original languageEnglish
JournalEuropean Journal of Heart Failure
DOIs
Publication statusAccepted/In press - 2021

Keywords

  • Cancer
  • Heart failure
  • Pregnancy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy'. Together they form a unique fingerprint.

Cite this