Rituximab in a childhood-onset idiopathic refractory chronic inflammatory demyelinating polyneuropathy

Adele D'Amico; Michela Catteruccia; Fabrizio De Benedetti; Marina Vivarelli; Manuela Colucci; Simona Cascioli; Enrico Bertini

doi:10.1016/j.ejpn.2011.08.002

Rituximab in a childhood-onset idiopathic refractory chronic inflammatory demyelinating polyneuropathy

Adele D'Amico, Michela Catteruccia, Fabrizio De Benedetti, Marina Vivarelli, Manuela Colucci, Simona Cascioli, Enrico Bertini

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

Childhood-onset chronic inflammatory demyelinating polyneuropathy (CIDP) are generally responsive to conventional immunosuppressant treatments. However about 20% of patients may be refractory to several treatments and the disease has poor outcome. Rituximab is becoming a promising treatment in selected adult cases of severe CIDPs. We report the effectiveness of Rituximab in a refractory childhood-onset CIDP and we suggest this treatment as an effective choice in unresponsive childhood CIDP.

Original language	English
Pages (from-to)	301-303
Number of pages	3
Journal	European Journal of Paediatric Neurology
Volume	16
Issue number	3
DOIs	https://doi.org/10.1016/j.ejpn.2011.08.002
Publication status	Published - May 2012

Keywords

CIPD
Polineuropathy
Rituximab

ASJC Scopus subject areas

Clinical Neurology
Pediatrics, Perinatology, and Child Health

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10.1016/j.ejpn.2011.08.002

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Rituximab in a childhood-onset idiopathic refractory chronic inflammatory demyelinating polyneuropathy. / D'Amico, Adele ; Catteruccia, Michela ; De Benedetti, Fabrizio ; Vivarelli, Marina ; Colucci, Manuela ; Cascioli, Simona ; Bertini, Enrico.

In: European Journal of Paediatric Neurology, Vol. 16, No. 3, 05.2012, p. 301-303.

Research output: Contribution to journal › Article › peer-review

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abstract = "Childhood-onset chronic inflammatory demyelinating polyneuropathy (CIDP) are generally responsive to conventional immunosuppressant treatments. However about 20% of patients may be refractory to several treatments and the disease has poor outcome. Rituximab is becoming a promising treatment in selected adult cases of severe CIDPs. We report the effectiveness of Rituximab in a refractory childhood-onset CIDP and we suggest this treatment as an effective choice in unresponsive childhood CIDP.",

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AU - D'Amico, Adele

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AU - De Benedetti, Fabrizio

AU - Vivarelli, Marina

AU - Colucci, Manuela

AU - Cascioli, Simona

AU - Bertini, Enrico

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AB - Childhood-onset chronic inflammatory demyelinating polyneuropathy (CIDP) are generally responsive to conventional immunosuppressant treatments. However about 20% of patients may be refractory to several treatments and the disease has poor outcome. Rituximab is becoming a promising treatment in selected adult cases of severe CIDPs. We report the effectiveness of Rituximab in a refractory childhood-onset CIDP and we suggest this treatment as an effective choice in unresponsive childhood CIDP.

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KW - Rituximab

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Rituximab in a childhood-onset idiopathic refractory chronic inflammatory demyelinating polyneuropathy

Abstract

Keywords

ASJC Scopus subject areas

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