Studio RMf della dominanza emisferica in destrimani e non destrimani

Translated title of the contribution: RMf study of hemispheric dominance in right handers and non-right handers

P. Vitali, N. Mavilio, D. Capello, M. Rosa, A. Ferrari, F. Levrero, A. Pilot, F. Nobili, G. Rodriguez

Research output: Contribution to journalArticlepeer-review

Abstract

Non invasive evaluation of hemispheric dominance for language is one of the most promising clinical applications of the functional Magnetic Resonance Imaging, particularly in patients candidate to neurosurgery. In this study two language tasks were performed in a healthy group of young volunteers (8 right-handed, 12 non right-handed):i) a phonemic fluency task and ii) a semantic judgement task. Among the statistically activated voxels in the two hemispheres, three asymmetry indexes (i.e. hemispheric, frontal, and temporoparietal) were computed in each subject and for each task. In summary, phonemic fluency strongly activated the frontal lobe, while semantic judgement caused a more widespread activation pattern, involving the medium temporal and angular gyri. Concerning the asymmetry indexes, the hemispheric and frontal indexes always showed main activation of the left hemisphere in right handers. Only one ambidextrous subject showed hemispheric and frontal right lateralisation in phonemic fluency. On the other hand, temporoparietal asymmetry index showed a mild right lateralisation in a right handers and a strong right lateralisation in a non-right hander. Therefore, functional Magnetic Resonance Imaging is sensitive and appropriate in the evaluation of language dominance. Use of asymmetry lobar indexes could better distinguish the contribute to hemispheric dominance between frontal and temporoparietal areas. Finally, localisation of the language-related areas could be useful to the neurosurgeon in the resection planning of neighbouring tissues.

Translated title of the contributionRMf study of hemispheric dominance in right handers and non-right handers
Original languageItalian
Pages (from-to)131-138
Number of pages8
JournalRivista di Neuroradiologia
Volume13
Issue number1
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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