Abstract
Stroke leaves many patients disabled even after rehabilitative training, representing a major cause of disability. Several approaches to improve outcomes have been attempted in recent years, with only relative benefit. Emerging evidences show a potential role of pharmacological intervention to enhance motor recovery after stroke. Contrasting evidence are coming from experimental and clinical studies, so far, and pharmacological intervention during rehabilitation represents a major controversial in neurorehabilitation. Dopaminergic stimulation appears as one of the most promising way to improve motor recovery. Subject of this paper will be the ratio underlying the clinical use of levodopa in chronic stroke patients, trying to outline the most convincing evidences about a potential role of this drug in rehabilitative strategies.
| Original language | English |
|---|---|
| Pages (from-to) | 243-249 |
| Number of pages | 7 |
| Journal | European Journal of Physical and Rehabilitation Medicine |
| Volume | 49 |
| Issue number | 2 |
| Publication status | Published - Apr 2013 |
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Keywords
- Neuronal plasticity.
- Rehabilitation
- Stroke
ASJC Scopus subject areas
- Rehabilitation
- Physical Therapy, Sports Therapy and Rehabilitation
Cite this
Role, indications and controversies of levodopa administration in chronic stroke patients. / Acler, M.; Manganotti, P.
In: European Journal of Physical and Rehabilitation Medicine, Vol. 49, No. 2, 04.2013, p. 243-249.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Role, indications and controversies of levodopa administration in chronic stroke patients
AU - Acler, M.
AU - Manganotti, P.
PY - 2013/4
Y1 - 2013/4
N2 - Stroke leaves many patients disabled even after rehabilitative training, representing a major cause of disability. Several approaches to improve outcomes have been attempted in recent years, with only relative benefit. Emerging evidences show a potential role of pharmacological intervention to enhance motor recovery after stroke. Contrasting evidence are coming from experimental and clinical studies, so far, and pharmacological intervention during rehabilitation represents a major controversial in neurorehabilitation. Dopaminergic stimulation appears as one of the most promising way to improve motor recovery. Subject of this paper will be the ratio underlying the clinical use of levodopa in chronic stroke patients, trying to outline the most convincing evidences about a potential role of this drug in rehabilitative strategies.
AB - Stroke leaves many patients disabled even after rehabilitative training, representing a major cause of disability. Several approaches to improve outcomes have been attempted in recent years, with only relative benefit. Emerging evidences show a potential role of pharmacological intervention to enhance motor recovery after stroke. Contrasting evidence are coming from experimental and clinical studies, so far, and pharmacological intervention during rehabilitation represents a major controversial in neurorehabilitation. Dopaminergic stimulation appears as one of the most promising way to improve motor recovery. Subject of this paper will be the ratio underlying the clinical use of levodopa in chronic stroke patients, trying to outline the most convincing evidences about a potential role of this drug in rehabilitative strategies.
KW - Neuronal plasticity.
KW - Rehabilitation
KW - Stroke
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UR - http://www.scopus.com/inward/citedby.url?scp=84881409623&partnerID=8YFLogxK
M3 - Article
VL - 49
SP - 243
EP - 249
JO - European Journal of Physical and Rehabilitation Medicine
JF - European Journal of Physical and Rehabilitation Medicine
SN - 1973-9087
IS - 2
ER -