Ruolo delle nuove ed avanzate modalità di studio RM nella diagnostica neuroradiologica dei gliomi cerebrali

Translated title of the contribution: Role of advanced MR imaging modalities in diagnosing cerebral gliomas

T. Scarabino, T. Popolizio, F. Trojsi, G. Giannatempo, S. Pollice, N. Maggialetti, A. Carriero, A. Di Costanzo, G. Tedeschi, U. Salvolini

Research output: Contribution to journalArticlepeer-review

Abstract

The objective of this study was to evaluate the potential role of newly developed, advanced magnetic resonance (MR) imaging techniques (spectroscopy, diffusion and perfusion imaging) in diagnosing brain gliomas, with special reference to histological typing and grading, treatment planning and posttreatment follow-up. Conventional MR imaging enables the detection and localisation of neoplastic lesions, as well as providing, in typical cases, some indication about their nature. However, it has limited sensitivity and specificity in evaluating histological type and grade, delineating margins and differentiating oedema, tumour and treatment side-effects. These limitations can be overcome by supplementing the morphological data obtained with conventional MR imaging with the metabolic, structural and perfusional information provided by new MR techniques that are increasingly becoming an integral part of routine MR studies. Incorporation of such new MR techniques can lead to more comprehensive and precise diagnoses that can better assist surgeons in determining prognosis and planning treatment strategies. In addition, the recent development of new, more effective, treatments for cerebral glioma strongly relies on morphofunctional MR imaging with its ability to provide a biological interpretation of these characteristically heterogeneous tumours.

Translated title of the contributionRole of advanced MR imaging modalities in diagnosing cerebral gliomas
Original languageItalian
Pages (from-to)448-460
Number of pages13
JournalRadiologia Medica
Volume114
Issue number3
DOIs
Publication statusPublished - Apr 2009

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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