TY - JOUR
T1 - Role of ambulatory blood pressure monitoring in resistant hypertension
AU - Grassi, Guido
AU - Bombelli, Michele
AU - Seravalle, Gino
AU - Brambilla, Gianmaria
AU - Dell'Oro, Raffaella
AU - Mancia, Giuseppe
PY - 2013/6
Y1 - 2013/6
N2 - Ambulatory blood pressure monitoring has gained growing popularity in the diagnosis and treatment of essential hypertension for several reasons, such as the lack of the so-called white-coat effect, the greater reproducibility as compared with clinic blood pressure, the ability to provide information on blood pressure phenomena of prognostic value and the closer relationship with the risk of cardiovascular morbidity and mortality. All the above-mentioned main features of ambulatory blood pressure monitoring are also true for resistant hypertension. In addition, however, in resistant hypertension, blood pressure monitoring allows one to precisely define the diagnosis of this clinical condition, by excluding the presence of white-coat hypertension, which is responsible for a consistent number of "false" resistant hypertensive cases. The approach also allows one to define the patterns of blood pressure variability in this clinical condition, as well as its relationships with target organ damage. Finally, it allows one to assess the effects of therapeutic interventions, such as renal nerves ablation, aimed at improving blood pressure control in this hypertensive state. The present paper will critically review the main features of ambulatory blood pressure monitoring in resistant hypertension, with particular emphasis on the diagnosis and treatment of this high-risk hypertensive state.
AB - Ambulatory blood pressure monitoring has gained growing popularity in the diagnosis and treatment of essential hypertension for several reasons, such as the lack of the so-called white-coat effect, the greater reproducibility as compared with clinic blood pressure, the ability to provide information on blood pressure phenomena of prognostic value and the closer relationship with the risk of cardiovascular morbidity and mortality. All the above-mentioned main features of ambulatory blood pressure monitoring are also true for resistant hypertension. In addition, however, in resistant hypertension, blood pressure monitoring allows one to precisely define the diagnosis of this clinical condition, by excluding the presence of white-coat hypertension, which is responsible for a consistent number of "false" resistant hypertensive cases. The approach also allows one to define the patterns of blood pressure variability in this clinical condition, as well as its relationships with target organ damage. Finally, it allows one to assess the effects of therapeutic interventions, such as renal nerves ablation, aimed at improving blood pressure control in this hypertensive state. The present paper will critically review the main features of ambulatory blood pressure monitoring in resistant hypertension, with particular emphasis on the diagnosis and treatment of this high-risk hypertensive state.
KW - ABPM
KW - Ambulatory blood pressure monitoring
KW - Blood pressure variability
KW - Organ damage
KW - Renal denervation
KW - Resistant hypertension
KW - White coat hypertension
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U2 - 10.1007/s11906-013-0349-0
DO - 10.1007/s11906-013-0349-0
M3 - Article
C2 - 23585237
AN - SCOPUS:84877837821
VL - 15
SP - 232
EP - 237
JO - Current Hypertension Reports
JF - Current Hypertension Reports
SN - 1522-6417
IS - 3
ER -