I MECCANISMI MOLECOLARI DELLA MEMORIA: RUOLO DEI RECETTORI AMPA

U. Scapagnini; F. Nicoletti; V. Bruno; A. Copani

I MECCANISMI MOLECOLARI DELLA MEMORIA: RUOLO DEI RECETTORI AMPA

Translated title of the contribution: Role of amino acid receptors in the molecular and transynaptic mechanisms of associative learnings

U. Scapagnini, F. Nicoletti, V. Bruno, A. Copani

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Abstract

Excitatory amino acid receptors are critically involved in the molecular and transynaptic mechanisms of associative learning. In particular, NMDA receptors are necessary for the induction of the learning process, whereas AMPA receptors mediate synaptic facilitation, a process by which neurons recognize a stimulus which had been previously learned, AMPA receptors are positively modulated by aniracetam, a nootropic drug which have been successfully tested in the experimental therapy of brain ageing.

Translated title of the contribution	Role of amino acid receptors in the molecular and transynaptic mechanisms of associative learnings
Original language	Italian
Pages (from-to)	535-538
Number of pages	4
Journal	Giornale di Gerontologia
Volume	41
Issue number	11
Publication status	Published - 1993

ASJC Scopus subject areas

Ageing
Geriatrics and Gerontology

Cite this

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abstract = "Excitatory amino acid receptors are critically involved in the molecular and transynaptic mechanisms of associative learning. In particular, NMDA receptors are necessary for the induction of the learning process, whereas AMPA receptors mediate synaptic facilitation, a process by which neurons recognize a stimulus which had been previously learned, AMPA receptors are positively modulated by aniracetam, a nootropic drug which have been successfully tested in the experimental therapy of brain ageing.",

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AU - Bruno, V.

AU - Copani, A.

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AB - Excitatory amino acid receptors are critically involved in the molecular and transynaptic mechanisms of associative learning. In particular, NMDA receptors are necessary for the induction of the learning process, whereas AMPA receptors mediate synaptic facilitation, a process by which neurons recognize a stimulus which had been previously learned, AMPA receptors are positively modulated by aniracetam, a nootropic drug which have been successfully tested in the experimental therapy of brain ageing.

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I MECCANISMI MOLECOLARI DELLA MEMORIA: RUOLO DEI RECETTORI AMPA

Abstract

ASJC Scopus subject areas

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