I MECCANISMI MOLECOLARI DELLA MEMORIA: RUOLO DEI RECETTORI AMPA

Translated title of the contribution: Role of amino acid receptors in the molecular and transynaptic mechanisms of associative learnings

U. Scapagnini, F. Nicoletti, V. Bruno, A. Copani

Research output: Contribution to journalArticlepeer-review

Abstract

Excitatory amino acid receptors are critically involved in the molecular and transynaptic mechanisms of associative learning. In particular, NMDA receptors are necessary for the induction of the learning process, whereas AMPA receptors mediate synaptic facilitation, a process by which neurons recognize a stimulus which had been previously learned, AMPA receptors are positively modulated by aniracetam, a nootropic drug which have been successfully tested in the experimental therapy of brain ageing.

Translated title of the contributionRole of amino acid receptors in the molecular and transynaptic mechanisms of associative learnings
Original languageItalian
Pages (from-to)535-538
Number of pages4
JournalGiornale di Gerontologia
Volume41
Issue number11
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

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