I MECCANISMI MOLECOLARI DELLA MEMORIA: RUOLO DEI RECETTORI AMPA

Excitatory amino acid receptors are critically involved in the molecular and transynaptic mechanisms of associative learning. In particular, NMDA receptors are necessary for the induction of the learning process, whereas AMPA receptors mediate synaptic facilitation, a process by which neurons recognize a stimulus which had been previously learned, AMPA receptors are positively modulated by aniracetam, a nootropic drug which have been successfully tested in the experimental therapy of brain ageing.