Abstract
Purpose: Low birth weight and accelerated postnatal growth appear to play a significant role in the pathogenesis of hypertension and cardiovascular disease in adulthood. The aim of the present study was to characterize the factors determining pulse wave velocity (PWV) in teenagers and, in particular, to verify the relationship with birth weight, postnatal growth, timing of adiposity rebound, lifestyle, and hemodynamic parameters. Methods: Carotid-femoral and carotid-radial pulse wave velocities of 558 healthy teenagers (age range: 16.2-19.9 years) were determined by means of a PulsePen tonometer. Birth weight and gestational age were obtained from obstetrical records, and data regarding postnatal growth were obtained from pediatric clinical records. Results: No change in aortic PWV was found in association with birth weight, postnatal growth, and timing of adiposity rebound. However, the study showed a strong association between accelerated growth from 0 to 12 months and carotid-radial PWV (trend: p =.02). Subjects with birth weight values
Original language | English |
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Pages (from-to) | 373-379 |
Number of pages | 7 |
Journal | Journal of Adolescent Health |
Volume | 51 |
Issue number | 4 |
DOIs | |
Publication status | Published - Oct 2012 |
Keywords
- Adiposity rebound
- Arterial stiffness
- Birth weight
- Childhood
- Pulse wave velocity
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Psychiatry and Mental health
- Public Health, Environmental and Occupational Health