Role of calcium in gamma interferon induction: Inhibition by calcium entry blockers

F. Dianzani, M. R. Capobianchi, J. Facchini

Research output: Contribution to journalArticlepeer-review

Abstract

Mitogen-induced gamma interferon production by human lymphoid cell cultures was studied in the presence of calcium entry blockers. A dose-dependent inhibition was found in the presence of drug concentrations down to 10-5 M. This finding shows that calcium flow through lymphocyte membranes after oxidation of membrane-bound galactose residues is also critical for triggering interferon production.

Original languageEnglish
Pages (from-to)964-965
Number of pages2
JournalJournal of Virology
Volume50
Issue number3
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Immunology

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