Role of distinct domains of Ia antigens in autologous and allogeneic mixed lymphocyte reactions.

F. Indiveri, M. Scudeletti, D. Pende, A. Barabino, C. Russo, M. A. Pellegrino, S. Ferrone

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Abstract

Murine monoclonal antibodies (MoAb) to distinct determinants of human Ia antigens and low doses of prednisone induce different effects on the autologous mixed lymphocyte reaction (MLR), stimulated by PHA-T cells or by non-T cells, and on allogeneic MLRs. These results suggest that distinct domains of Ia antigens and/or mechanisms are involved in these types of MLRs.

Original languageEnglish
Pages (from-to)95-100
Number of pages6
JournalBehring Institute Mitteilungen
Issue number72
Publication statusPublished - May 1983

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Indiveri, F., Scudeletti, M., Pende, D., Barabino, A., Russo, C., Pellegrino, M. A., & Ferrone, S. (1983). Role of distinct domains of Ia antigens in autologous and allogeneic mixed lymphocyte reactions. Behring Institute Mitteilungen, (72), 95-100.