Role of endoscopy and nutritional support in advanced esophageal cancer

Research output: Chapter in Book/Report/Conference proceedingChapter


More than half of patients affected by esophageal cancer have inoperable disease at presentation. Dysphagia relief and nutritional support assume primary importance in this setting. Palliation has become, for the most part, an area of endoscopic pertinence. Stent placement and brachytherapy are currently the most widely used and best evidence-based options. Other modalities, such as photodynamic therapy, Nd:YAG laser therapy, argon plasma coagulation, cryospray ablation and local injection of chemotherapeutic agents, are being evaluated as alternative or complementary methods of palliation. The combination of different modalities is feasible and it may enhance the efficacy of each technique and make up for the shortcomings. A multidisciplinary and personalized approach is, therefore, recommended in order to ensure the best management for each patient. We review here the role of these techniques in the palliation of inoperable esophageal cancer and offer the pros and cons of each, as well as future prospects.

Original languageEnglish
Title of host publicationEsophageal Cancer and Barrett's Esophagus
PublisherWiley Blackwell
Number of pages12
ISBN (Electronic)9781118655153
ISBN (Print)9781118655207
Publication statusPublished - Dec 12 2015


  • Argon plasma
  • Brachytherapy
  • Cryospray
  • Esophageal cancer
  • Nd:YAG
  • Palliation
  • Photodynamic
  • Stent

ASJC Scopus subject areas

  • Medicine(all)


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