Role of HPV DNA testing in modern gynaecological practice

Guglielmo Ronco, Paolo Giorgi Rossi

Research output: Contribution to journalReview articlepeer-review

Abstract

The identification of some types of human papillomavirus (HPV) as necessary, but not sufficient, cause of cervical cancer has suggested the use of HPV testing in cervical cancer prevention. A large number of studies has provided evidence supporting its application (1) as primary screening test, (2) for triaging borderline cytology, (3) for follow-up after positive primary test but no abnormal histology and (4) as a test of cure. They also allowed a reasonably good definition of the appropriate policies and protocols, leading to the delivery of evidence-based guidelines resulting from a systematic review of the literature. In this chapter, we present a critical analysis of the recommendations of the main European and North American guidelines relative to industrialised countries.

Original languageEnglish
Pages (from-to)107-118
Number of pages12
JournalBest Practice and Research: Clinical Obstetrics and Gynaecology
Volume47
DOIs
Publication statusPublished - Feb 1 2018

Keywords

  • Cervical cancer
  • Follow-up
  • Human papillomavirus
  • Primary test
  • Screening
  • Test of cure

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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