Role of in vitro testing in food allergy

Stefania Arasi; Simona Barni; Carla Mastrorilli; Pasquale Comberiati; Fernanda Chiera; Umberto Pelosi; Francesco Paravati; Davide Caimmi

doi:10.1111/pai.13342

Role of in vitro testing in food allergy

Stefania Arasi, Simona Barni, Carla Mastrorilli, Pasquale Comberiati, Fernanda Chiera, Umberto Pelosi, Francesco Paravati, Davide Caimmi

Research output: Contribution to journal › Article › peer-review

Abstract

Oral food challenges remain the gold standard for the diagnosis of food allergy. Nevertheless, the allergy workup is based on the presence of a clinical history, which is evocative of an immune-allergic reaction, and the first assessment is usually the performance of skin prick tests. Based on these results, allergists are used to evaluate the presence of serum-specific IgE, which are today the most commonly prescribed in vitro test for the evaluation of a possible food allergy. Other in vitro tests include the basophil activation test, that is becoming more and more employed by clinicians and not only by researchers, and the evaluation of serum IgG4, which is still an issue of debate in the allergy community. The present paper reviews the use of these in vitro tests for the diagnosis of food allergy.

Original language	English
Pages (from-to)	36-38
Number of pages	3
Journal	Pediatric Allergy and Immunology
Volume	31
Issue number	S26
DOIs	https://doi.org/10.1111/pai.13342
Publication status	Published - Nov 2020

Keywords

basophil activation test
component resolved diagnostics
food allergy
IgE-mediated
IgG
specific IgE

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Immunology and Allergy
Immunology

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10.1111/pai.13342

Cite this

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title = "Role of in vitro testing in food allergy",

abstract = "Oral food challenges remain the gold standard for the diagnosis of food allergy. Nevertheless, the allergy workup is based on the presence of a clinical history, which is evocative of an immune-allergic reaction, and the first assessment is usually the performance of skin prick tests. Based on these results, allergists are used to evaluate the presence of serum-specific IgE, which are today the most commonly prescribed in vitro test for the evaluation of a possible food allergy. Other in vitro tests include the basophil activation test, that is becoming more and more employed by clinicians and not only by researchers, and the evaluation of serum IgG4, which is still an issue of debate in the allergy community. The present paper reviews the use of these in vitro tests for the diagnosis of food allergy.",

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AU - Arasi, Stefania

AU - Barni, Simona

AU - Mastrorilli, Carla

AU - Comberiati, Pasquale

AU - Chiera, Fernanda

AU - Pelosi, Umberto

AU - Paravati, Francesco

AU - Caimmi, Davide

PY - 2020/11

Y1 - 2020/11

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Role of in vitro testing in food allergy

Abstract

Keywords

ASJC Scopus subject areas

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