Role of macrophage metalloelastase in gut inflammation

Sylvia L F Pender, C. K F Li, A. D I Sabatino, T. T. Macdonald, M. G. Buckley

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Matrix metalloproteinases (MMPs) are involved in a number of physiological and pathologic processes including the inflammation found in IBD. We have shown that MMP-3 is upregulated in Crohn's disease and in ulcerative colitis. This study shows a potential role for MMP-12 in these idiopathic diseases.

Original languageEnglish
Title of host publicationAnnals of the New York Academy of Sciences
Pages386-388
Number of pages3
Volume1072
DOIs
Publication statusPublished - 2006

Publication series

NameAnnals of the New York Academy of Sciences
Volume1072
ISSN (Print)00778923
ISSN (Electronic)17496632

Fingerprint

Matrix Metalloproteinase 12
Physiological Phenomena
Matrix Metalloproteinase 3
Pathologic Processes
Matrix Metalloproteinases
Ulcerative Colitis
Crohn Disease
Inflammation

Keywords

  • Immune response
  • Inflammatory bowel diseases
  • Intestine
  • Macrophages
  • Matrix metalloproteinase
  • Tissue inflammation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Pender, S. L. F., Li, C. K. F., Sabatino, A. D. I., Macdonald, T. T., & Buckley, M. G. (2006). Role of macrophage metalloelastase in gut inflammation. In Annals of the New York Academy of Sciences (Vol. 1072, pp. 386-388). (Annals of the New York Academy of Sciences; Vol. 1072). https://doi.org/10.1196/annals.1326.019

Role of macrophage metalloelastase in gut inflammation. / Pender, Sylvia L F; Li, C. K F; Sabatino, A. D I; Macdonald, T. T.; Buckley, M. G.

Annals of the New York Academy of Sciences. Vol. 1072 2006. p. 386-388 (Annals of the New York Academy of Sciences; Vol. 1072).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pender, SLF, Li, CKF, Sabatino, ADI, Macdonald, TT & Buckley, MG 2006, Role of macrophage metalloelastase in gut inflammation. in Annals of the New York Academy of Sciences. vol. 1072, Annals of the New York Academy of Sciences, vol. 1072, pp. 386-388. https://doi.org/10.1196/annals.1326.019
Pender SLF, Li CKF, Sabatino ADI, Macdonald TT, Buckley MG. Role of macrophage metalloelastase in gut inflammation. In Annals of the New York Academy of Sciences. Vol. 1072. 2006. p. 386-388. (Annals of the New York Academy of Sciences). https://doi.org/10.1196/annals.1326.019
Pender, Sylvia L F ; Li, C. K F ; Sabatino, A. D I ; Macdonald, T. T. ; Buckley, M. G. / Role of macrophage metalloelastase in gut inflammation. Annals of the New York Academy of Sciences. Vol. 1072 2006. pp. 386-388 (Annals of the New York Academy of Sciences).
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